Rabbit anti-Rat Sodium-dependent Multi-Vitamin Transporter Polyclonal Antibody | anti-SLC5A6 antibody
Sodium-dependent Multi-Vitamin Transporter (SMVT)
Gene Names
SLC5A6; SMVT
Reactivity
Rat
Applications
ELISA, Western Blot
Purity
Affinity PurifiedPurified by immunoaffinity chromatography.
Synonyms
Sodium-dependent Multi-Vitamin Transporter; Polyclonal Antibody; Sodium-dependent Multi-Vitamin Transporter (SMVT); Anti -Sodium-dependent Multi-Vitamin Transporter (SMVT); anti-SLC5A6 antibody
Host
Rabbit
Reactivity
Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes rat SMVT. Species Sequence Homology: human, 100%; mouse, 95%; rabbit, 80%
Purity/Purification
Affinity Purified
Purified by immunoaffinity chromatography.
Purified by immunoaffinity chromatography.
Form/Format
Supplied as a lyophilized powder from PBS, 0.1% BSA. Reconstititue with 100ul sterile PBS.
Applicable Applications for anti-SLC5A6 antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes
Suitable for use in ELISA and Western Blot.
Dilution: ELISA: 0.5-1ug/ml
Western Blot: 1-10ug/ml (ECL)
Dilution: ELISA: 0.5-1ug/ml
Western Blot: 1-10ug/ml (ECL)
Immunogen
Synthetic peptide corresponding to 22aa from the N-terminus, extracellular domain of rat SMVT, conjugated to KLH.
Preparation and Storage
Lyophilized powder may be stored at -20 degree C. Stable for 12 months at -20 degree C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Reconstituted product is stable for 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Related Product Information for anti-SLC5A6 antibody
A sodium-dependent transport system is responsible for the transfer and distribution of vitamins to different parts of the body, the transfer includes vitamins like pantothenate, biotin and ascorbic acid etc, These transporters belong to Solute Carrier family (SLC). Since vitamins are required for essential metabolic processes in all mammalian cells, such cells have developed intrinsic mechanisms to active accumulation of essential vitamins. Thus transporters help these cells to fulfill their requirement, they include Sodium-dependent Multi-Vitamin Transporter (SMVT), Sodium-dependent Vitamin-C Transporter (SVCT) 1 & 2 and Creatine Transporter (CRT1/ CT1). The other vitamin transporters from SLC family include Thiamine Transporter Protein 1 (THTR1), Folate Transporter or Reduced Folate Carrier 1 (RFC1), Thyroid Iodide Transporter (TIT) and Taurine Transporter (TAU) etc. Sodium-dependent Multi-Vitamin Transporter (SMVT), a 635aa protein in rat and human (gene SLC5A6) is responsible for transplacental transfer of vitamins pantothenate, biotin and the essential metabolite lipoate. SMVT shows homology to other known sodium-dependent nutrient transporters, including bacterial pantothenate permease, mammalian iodide transporter, glucose transporter 1 & 2. Quantitatively, the absorptive tissues like the intestinal mucosa, kidney and placenta have very high amounts of SMVT-specific mRNA. Significant amount is also seen in liver, brain and heart.
Product Categories/Family for anti-SLC5A6 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
68,642 Da
NCBI Official Full Name
sodium-dependent multi-vitamin transporter
NCBI Official Synonym Full Names
solute carrier family 5 (sodium-dependent vitamin transporter), member 6
NCBI Official Symbol
SLC5A6
NCBI Official Synonym Symbols
SMVT
NCBI Protein Information
sodium-dependent multivitamin transporter; OTTHUMP00000122593; OTTHUMP00000201025; solute carrier family 5 member 6; Na+-dependent multivitamin transporter; Na(+)-dependent multivitamin transporter
UniProt Protein Name
Sodium-dependent multivitamin transporter
Protein Family
UniProt Gene Name
SLC5A6
UniProt Synonym Gene Names
SMVT
UniProt Entry Name
SC5A6_HUMAN
Uniprot Description
SLC5A6: Transports pantothenate, biotin and lipoate in the presence of sodium. Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
Protein type: Membrane protein, multi-pass; Transporter; Transporter, SLC family; Membrane protein, integral
Chromosomal Location of Human Ortholog: 2p23
Cellular Component: membrane; brush border membrane; integral to plasma membrane; plasma membrane; vesicle membrane
Molecular Function: sodium-dependent multivitamin transmembrane transporter activity
Biological Process: pantothenate transport; vitamin metabolic process; transport; pantothenate metabolic process; sodium ion transport; biotin transport; transmembrane transport; water-soluble vitamin metabolic process; biotin metabolic process
Research Articles on SLC5A6
Similar Products
Product Notes
The SLC5A6 slc5a6 (Catalog #AAA612594) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Sodium-dependent Multi-Vitamin Transporter (SMVT) reacts with Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Sodium-dependent Multi-Vitamin Transporter can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB). Suitable for use in ELISA and Western Blot. Dilution: ELISA: 0.5-1ug/ml Western Blot: 1-10ug/ml (ECL). Researchers should empirically determine the suitability of the SLC5A6 slc5a6 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Sodium-dependent Multi-Vitamin Transporter, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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