Rabbit anti-Human SOCS5 Polyclonal Antibody | anti-SOCS5 antibody

SOCS5 (Suppressor of Cytokine Signaling 5, SOCS-5, Cytokine-inducible SH2 Protein 6, CIS6, CIS-6, CISH6, Cytokine-inducible SH2-containing Protein 5, CISH5, KIAA0671) (HRP)

Cat. Num. AAA6394755

• Gene Names: SOCS5; CIS6; CISH6; Cish5; SOCS-5
• Reactivity: Human
• Applications: Western Blot
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: SOCS5; Polyclonal Antibody; SOCS5 (Suppressor of Cytokine Signaling 5; SOCS-5; Cytokine-inducible SH2 Protein 6; CIS6; CIS-6; CISH6; Cytokine-inducible SH2-containing Protein 5; CISH5; KIAA0671) (HRP); anti-SOCS5 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Recognizes human SOCS5.
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Horseradish Peroxidase (HRP).
• Sequence Length: 4422

• Applicable Applications for anti-SOCS5 antibody: Western Blot (WB)
• Application Notes: Applications are based on unconjugated antibody.
• Immunogen: Full length human SOCS5, aa1-536 (NP_054730.1).
• Immunogen Sequence: MDKVGKMWNNFKYRCQNLFGHEGGSRSENVDMNSNRCLSVKEKNISIGDSTPQQQSSPLRENIALQLGLSPSKNSSRRNQNCATEIPQIVEISIEKDNDSCVTPGTRLARRDSYSRHAPWGGKKKHSCSTKTQSSLDADKKFGRTRSGLQRRERRYGVSSVHDMDSVSSRTVGSRSLRQRLQDTVGLCFPMRTYSKQSKPLFSNKRKIHLSELMLEKCPFPAGSDLAQKWHLIKQHTAPVSPHSTFFDTFDPSLVSTEDEEDRLRERRRLSIEEGVDPPPNAQIHTFEATAQVNPLYKLGPKLAPGMTEISGDSSAIPQANCDSEEDTTTLCLQSRRQKQRQISGDSHTHVSRQGAWKVHTQIDYIHCLVPDLLQITGNPCYWGVMDRYEAEALLEGKPEGTFLLRDSAQEDYLFSVSFRRYNRSLHARIEQWNHNFSFDAHDPCVFHSSTVTGLLEHYKDPSSCMFFEPLLTISLNRTFPFSLQYICRAVICRCTTYDGIDGLPLPSMLQDFLKEYHYKQKVRVRWLEREPVKAK
• Conjugate: HRP
• Note: Preservative Free
• Preparation and Storage: Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Note: Sodium azide is a potent inhibitor of peroxidase and should not be added to HRP conjugates. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(Western Blot analysis of SOCS5 expression in transfected 293T cell line by SOCS5 polyclonal antibody. Lane 1: SOCS5 transfected lysate (61.2kD). Lane 2: Non-transfected lysate. )

Product Categories/Family for anti-SOCS5 antibody

Antibodies; SOCS

NCBI and Uniprot Product Information

• NCBI GI #: 41349444
• NCBI GeneID: 9655
• NCBI Accession #: NM_014011.4
• NCBI GenBank Nucleotide #: NM_014011
• UniProt Accession #: O75159
• NCBI Official Full Name: Homo sapiens suppressor of cytokine signaling 5 (SOCS5), transcript variant 1, mRNA
• NCBI Official Synonym Full Names: suppressor of cytokine signaling 5
• NCBI Official Symbol: SOCS5
• NCBI Official Synonym Symbols: CIS6; CISH6; Cish5; SOCS-5
• NCBI Protein Information: suppressor of cytokine signaling 5
• UniProt Protein Name: Suppressor of cytokine signaling 5
• Protein Family: Suppressor of cytokine signaling
• UniProt Gene Name: SOCS5
• UniProt Synonym Gene Names: CIS6; CISH5; CISH6; KIAA0671; SOCS-5; CIS-6
• UniProt Entry Name: SOCS5_HUMAN

NCBI Description

The protein encoded by this gene contains a SH2 domain and a SOCS BOX domain. The protein thus belongs to the suppressor of cytokine signaling (SOCS) family, also known as STAT-induced STAT inhibitor (SSI) protein family. SOCS family members are known to be cytokine-inducible negative regulators of cytokine signaling. The specific function of this protein has not yet been determined. Two alternatively spliced transcript variants encoding an identical protein have been reported. [provided by RefSeq, Jul 2008]