Mouse anti-Human SNX13 Polyclonal Antibody | anti-Snx13 antibody

SNX13 (Sorting Nexin-13, KIAA0713, RGS Domain- and PHOX Domain-containing Protein, RGS-PX1)

Cat. Num. AAA6004609

• Gene Names: Snx13; Rgs-px1; mKIAA0713
• Reactivity: Human
• Applications: Western Blot, Immunofluorescence
• Purity: Affinity Purified; Purified by Protein A affinity chromatography.
• Synonyms: SNX13; Polyclonal Antibody; SNX13 (Sorting Nexin-13; KIAA0713; RGS Domain- and PHOX Domain-containing Protein; RGS-PX1); Anti -SNX13 (Sorting Nexin-13; anti-Snx13 antibody

• Host: Mouse
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Recognizes human SNX13.
• Purity/Purification: Affinity Purified; Purified by Protein A affinity chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2.
• Sequence: MLTEASLSIWGWGSLGIVLFLITFGPFVIFYLTFYILCFVGGGLVVTLLFGKTNSEKYLEQCEHSFLPPTSPGVPKCLEEMKREARTIKIDRRLTGANIIDEPLQQVIQFSLRDYVQYWYYTLSDDESFLLEIRQTLQNALIQFATRSKEIDWQPYFTTRIVDDFGTHLRVFRKAQQKITEKDDQVKGTAEDLVDTFFEVEVEMEKEVCRDLVCTSPKDEEGFLRDLCEVLLYLLLPPGDFQNKIMRYFVREILARGILLPLINQLSDPDYINQYVIWMIRDSNCNYEAFMNIIKLSDNIGELEAVRDKAAEELQYLRSLDTAGDDINTIKNQINSLLFVKKVCDSRIQRLQSGKEINTVKLAANFGKLCTVPLDSILVDNVALQFFMDYMQQTGGQAHLFFWMTVEGYRVTAQQQLEVLLSRQRDGKHQTNQTKGLLRAAAVGIYEQYLSEKASPRVTVDDYLVAKLADTLNHEDPTPEIFDDIQRKVYELMLRDERFYPSFRQNALYVRMLAELDMLKDPSFRGSDDGDGESFNGSPTGSINLSLDDLSNVSSDDSVQLHAYISDTGVCNDHGKTYALYAITVHRRNLNSEEMWKTYRRYSDFHDFHMRITEQFESLSSILKLPGKKTFNNMDRDFLEKRKKDLNAYLQLLLAPEMMKASPALAHYVYDFLENKAYSKGKGDFARKMDTFVNPLRNSMRNVSNAVKSLPDNLAEGMTKMSDNMGKMSERLGQDIKQSFFKVPPLIPKTDSDPEHRRVSAQLDDNVDDNIPLRVMLLLMDEVFDLKERNQWLRRNIKNLLQQLIRATYGDTINRKIVDHVDWMTSPEQVADSVKRFRDAFWPNGILAEAVPCRDKSIRMRTRVAGKTKLLAIMPDELKHIIGAETTRKGILRVFEMFQHNQLNRRMVYVFLEGFLETLFPQYKFRELFNKLHSRSKQMQKYKQKLQTTQAPSLQKR

• Applicable Applications for anti-Snx13 antibody: Western Blot (WB), Immunofluorescence (IF)
• Application Notes: Suitable for use in Immunofluorescence and Western Blot.; Dilution: Immunofluorescence: 10ug/ml
• Immunogen: Full length human SNX13, aa1-957 (AAH45667.1).
• Preparation and Storage: May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(Western Blot analysis of SNX13 expression in transfected 293T cell line by SNX13 polyclonal antibody. Lane 1: SNX13 transfected lysate (105.27kD). Lane 2: Non-transfected lysate.)

Immunofluorescence (IF)

(Immunofluorescence of purified antibody to SNX13 on HeLa cell. [antibody concentration 10ug/ml])

Product Categories/Family for anti-Snx13 antibody

Antibodies; Abs to SNX Proteins

NCBI and Uniprot Product Information

• NCBI GI #: 224994275
• NCBI GeneID: 217463
• NCBI Accession #: NP_001014973.2
• NCBI GenBank Nucleotide #: NM_001014973.2
• UniProt Accession #: Q6PHS6
• Molecular Weight: 110,819 Da
• NCBI Official Full Name: sorting nexin-13
• NCBI Official Synonym Full Names: sorting nexin 13
• NCBI Official Symbol: Snx13
• NCBI Official Synonym Symbols: Rgs-px1; mKIAA0713
• NCBI Protein Information: sorting nexin-13
• UniProt Protein Name: Sorting nexin-13
• Protein Family: Sorting nexin
• UniProt Gene Name: Snx13
• UniProt Entry Name: SNX13_MOUSE

Uniprot Description

SNX13: May be involved in several stages of intracellular trafficking. May play a role in endosome homeostasis. Acts as a GAP for Galphas. Belongs to the sorting nexin family. 2 isoforms of the human protein are produced by alternative splicing.

Cellular Component: membrane; early endosome; endosome

Molecular Function: lipid binding; phosphoinositide binding; phosphatidylinositol 3-phosphate binding

Biological Process: intracellular protein transport; protein transport; transport; positive regulation of GTPase activity; negative regulation of signal transduction