Rabbit anti-Human SNRPB Polyclonal Antibody | anti-SNRPB antibody

SNRPB Rabbit Polyclonal

Cat. Num. AAA7604303

• Gene Names: SNRPB; COD; CCMS; SNRPB1; SmB/B'; Sm-B/B'; snRNP-B; SmB/SmB'
• Reactivity: Human
• Applications: ELISA, Western Blot, Immunohistochemistry
• Purity: >=95% as determined by SDS-PAGE; Immunogen Affinity Purified
• Synonyms: SNRPB; Polyclonal Antibody; SNRPB Rabbit Polyclonal; anti-SNRPB antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: >=95% as determined by SDS-PAGE; Immunogen Affinity Purified
• Form/Format: Liquid
• Sequence Length: 240

• Applicable Applications for anti-SNRPB antibody: ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
• Immunogen: Small nuclear ribonucleoprotein polypeptides B and B1
• Preparation and Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20 degree C for 24 months (Avoid repeated freeze / thaw cycles.)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human cervical cancer tissue slide using MBS7604303 (SNRPB Antibody) at dilution of 1:50)

Western Blot (WB)

(HepG2 cells were subjected to SDS PAGE followed by western blot with MBS7604303 (SNRPB antibody) at dilution of 1:500)

NCBI and Uniprot Product Information

• NCBI GI #: 48146055
• NCBI GeneID: 6628
• UniProt Accession #: P14678; Q15490; Q6IB35; Q9UIS5
• Molecular Weight: 30,032 Da
• NCBI Official Full Name: SNRPB
• NCBI Official Synonym Full Names: small nuclear ribonucleoprotein polypeptides B and B1
• NCBI Official Symbol: SNRPB
• NCBI Official Synonym Symbols: COD; CCMS; SNRPB1; SmB/B'; Sm-B/B'; snRNP-B; SmB/SmB'
• NCBI Protein Information: small nuclear ribonucleoprotein-associated proteins B and B'
• UniProt Protein Name: Small nuclear ribonucleoprotein-associated proteins B and B'
• Protein Family: Small nuclear ribonucleoprotein-associated protein
• UniProt Gene Name: SNRPB
• UniProt Synonym Gene Names: COD; SNRPB1; snRNP-B; Sm-B/B'; SmB/B'
• UniProt Entry Name: RSMB_HUMAN

NCBI Description

The protein encoded by this gene is one of several nuclear proteins that are found in common among U1, U2, U4/U6, and U5 small ribonucleoprotein particles (snRNPs). These snRNPs are involved in pre-mRNA splicing, and the encoded protein may also play a role in pre-mRNA splicing or snRNP structure. Autoantibodies from patients with systemic lupus erythematosus frequently recognize epitopes on the encoded protein. Two transcript variants encoding different isoforms (B and B') have been found for this gene. [provided by RefSeq, Jul 2008]

Uniprot Description

Core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. As part of the U7 snRNP it is involved in histone 3'-end processing.