Western Blot (WB)
(Western blot analysis of SNRNP40 Antibody (Center) in Neuro-2a cell line lysates (35ug/lane).SNRNP40 (arrow) was detected using the purified Pab.)
Rabbit SNRNP40 Polyclonal Antibody | anti-SNRNP40 antibody
SNRNP40 Antibody (Center)
Western Blot (WB)
(Western blot analysis of SNRNP40 Antibody (Center) in Neuro-2a cell line lysates (35ug/lane).SNRNP40 (arrow) was detected using the purified Pab.)
Western Blot (WB)
(Western blot analysis of SNRNP40 Antibody (Center) in Neuro-2a cell line lysates (35ug/lane).SNRNP40 (arrow) was detected using the purified Pab.)
Immunohistochemistry (IHC)
(SNRNP40 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human prostate carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the SNRNP40 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)
Immunohistochemistry (IHC)
(SNRNP40 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human prostate carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the SNRNP40 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)
Higa, L.A., et al. Nat. Cell Biol. 8(11):1277-1283(2006)
Liu, S., et al. RNA 12(7):1418-1430(2006)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a component of the U5 small nuclear ribonucleoprotein (snRNP) particle. The U5 snRNP is part of the spliceosome, a multiprotein complex that catalyzes the removal of introns from pre-messenger RNAs. [provided by RefSeq, Jul 2008]
Uniprot Description
WDR57: a nuclear WD40 repeat protein involved in pre-mRNA processing. A member of the spliceosome C complex. WD40 repeats are found in a number of eukaryotic proteins that coordinate multi-protein complex assemblies. WD40 proteins are implicated in many functions including adaptor/regulatory modules in signal transduction, RNA processing and cytoskeleton assembly.
Protein type: RNA-binding; Spliceosome; RNA splicing
Chromosomal Location of Human Ortholog: 1p35.2
Cellular Component: nucleoplasm; small nucleolar ribonucleoprotein complex; snRNP U5; cytoplasm
Molecular Function: protein binding
Biological Process: RNA processing; RNA splicing, via transesterification reactions; nuclear mRNA splicing, via spliceosome; RNA splicing; gene expression
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Product Notes
The SNRNP40 snrnp40 (Catalog #AAA9209967) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 122-149. The SNRNP40 Antibody (Center) reacts with Human (Predicted Reactivity: Bovine, Mouse) and may cross-react with other species as described in the data sheet. AAA Biotech's SNRNP40 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC). WB~~1:1000. Researchers should empirically determine the suitability of the SNRNP40 snrnp40 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SNRNP40, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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