Western Blot (WB)
(Western blot analysis of SNRK (arrow) using rabbit polyclonal SNRK Antibody (Center) . 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the SNRK gene.)
Rabbit anti-Human SNRK Polyclonal Antibody | anti-SNRK antibody
SNRK, ID (SNRK, KIAA0096, SNFRK, SNF-related serine/threonine-protein kinase, SNF1-related kinase)
Purified by Protein A affinity chromatography.
Purified by Protein A affinity chromatography.
Dilution: ELISA: 1:1,000
Western blotting 1:100-500
Immunohistochemistry: 1:10-50
Western Blot (WB)
(Western blot analysis of SNRK (arrow) using rabbit polyclonal SNRK Antibody (Center) . 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the SNRK gene.)
Western Blot (WB)
(Western blot analysis of SNRK (arrow) using rabbit polyclonal SNRK Antibody (Center) . 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the SNRK gene.)
Immunohistochemistry (IHC)
(SNRK Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human testis tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of SNRK Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)
Immunohistochemistry (IHC)
(SNRK Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human testis tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of SNRK Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)
NCBI and Uniprot Product Information
NCBI Description
SNRK is a member of the sucrose nonfermenting (SNF)-related kinase family of serine/threonine kinases (Kertesz et al., 2002 [PubMed 12234663]).[supplied by OMIM, Apr 2009]
Uniprot Description
Function: May play a role in hematopoietic cell proliferation or differentiation. Potential mediator of neuronal apoptosis. Ref.1 Ref.2
Catalytic activity: ATP + a protein = ADP + a phosphoprotein.
Cofactor: Magnesium.
Enzyme regulation: Activated by phosphorylation on Thr-173. Ref.2
Subcellular location: Nucleus
By similarity.
Tissue specificity: Expressed in hematopoietic progenitor cells and leukemic cell lines. Weakly expressed in the testis. Ref.1 Ref.10
Post-translational modification: Autophosphorylated. Phosphorylation on Thr-173 by STK11/LKB1 in complex with STE20-related adapter-alpha (STRADA) pseudo kinase and CAB39. Ref.1 Ref.2
Sequence similarities: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.Contains 1 protein kinase domain.Contains 1 UBA domain.
Sequence caution: The sequence BAA07744.2 differs from that shown. Reason: Erroneous initiation. The sequence CAH18415.1 differs from that shown. Reason: Erroneous initiation.
Research Articles on SNRK
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Product Notes
The SNRK snrk (Catalog #AAA649412) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The SNRK, ID (SNRK, KIAA0096, SNFRK, SNF-related serine/threonine-protein kinase, SNF1-related kinase) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's SNRK can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC). Suitable for use in Western Blot, Immunohistochemistry, ELISA Dilution: ELISA: 1:1,000 Western blotting 1:100-500 Immunohistochemistry: 1:10-50. Researchers should empirically determine the suitability of the SNRK snrk for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SNRK, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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