Rabbit anti-Human SNAP23 Polyclonal Antibody | anti-SNAP23 antibody

SNAP23 Antibody

Cat. Num. AAA9507480

• Gene Names: SNAP23; SNAP-23; SNAP23A; SNAP23B; HsT17016
• Reactivity: Human
• Applications: Western Blot, ELISA
• Purity: Affinity-purified from rabbit antiserum by affinity-chromatography using peptide.
• Synonyms: SNAP23; Polyclonal Antibody; SNAP23 Antibody; anti-SNAP23 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Specificity: SNAP23 Antibody detects endogenous levels of SNAP23 protein.
• Purity/Purification: Affinity-purified from rabbit antiserum by affinity-chromatography using peptide.
• Form/Format: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Concentration: 1 mg/ml (varies by lot)
• Sequence Length: 158

• Applicable Applications for anti-SNAP23 antibody: Western Blot (WB), ELISA (EIA)
• Application Notes: WB: 1:500~1:1000; ELISA: 1:10000
• Target Modification: Unmodified/Total
• Immunogen: The antiserum was produced against synthesized peptide derived from the C-terminal region of human SNAP23.
• Immunogen Range: 151-200
• Preparation and Storage: Stable at -20 degree C for at least 1 year.

Western Blot (WB)

(Western blot analysis of lysate from HepG2 cells, using SNAP23 Antibody.)

NCBI and Uniprot Product Information

• NCBI GI #: 18765729
• NCBI GeneID: 8773
• NCBI Accession #: NP_003816.2
• NCBI GenBank Nucleotide #: NM_003825.3
• UniProt Accession #: O00161; O00162; Q13602; Q6IAE3
• Molecular Weight: 23 kDa
• NCBI Official Full Name: synaptosomal-associated protein 23 isoform SNAP23A
• NCBI Official Synonym Full Names: synaptosome associated protein 23
• NCBI Official Symbol: SNAP23
• NCBI Official Synonym Symbols: SNAP-23; SNAP23A; SNAP23B; HsT17016
• NCBI Protein Information: synaptosomal-associated protein 23
• UniProt Protein Name: Synaptosomal-associated protein 23
• Protein Family: Synaptosomal-associated protein
• UniProt Gene Name: SNAP23
• UniProt Synonym Gene Names: SNAP-23

NCBI Description

Specificity of vesicular transport is regulated, in part, by the interaction of a vesicle-associated membrane protein termed synaptobrevin/VAMP with a target compartment membrane protein termed syntaxin. These proteins, together with SNAP25 (synaptosome-associated protein of 25 kDa), form a complex which serves as a binding site for the general membrane fusion machinery. Synaptobrevin/VAMP and syntaxin are believed to be involved in vesicular transport in most, if not all cells, while SNAP25 is present almost exclusively in the brain, suggesting that a ubiquitously expressed homolog of SNAP25 exists to facilitate transport vesicle/target membrane fusion in other tissues. The protein encoded by this gene is structurally and functionally similar to SNAP25 and binds tightly to multiple syntaxins and synaptobrevins/VAMPs. It is an essential component of the high affinity receptor for the general membrane fusion machinery and is an important regulator of transport vesicle docking and fusion. Two alternative transcript variants encoding different protein isoforms have been described for this gene. [provided by RefSeq, Jul 2008]

Uniprot Description

Essential component of the high affinity receptor for the general membrane fusion machinery and an important regulator of transport vesicle docking and fusion.