Western Blot (WB)
(Anti- SNAI3 Picoband antibody, MBS177967, Western blottingAll lanes: Anti SNAI3 (MBS177967) at 0.5ug/mlWB: MCF-7 Whole Cell Lysate at 40ugPredicted bind size: 32KDObserved bind size: 32KD )
anti-Human SNAI3 Polyclonal Antibody | anti-SNAI3 antibody
Anti-SNAI3 Antibody
Gene Names
SNAI3; SMUC; SNAIL3; ZNF293; Zfp293
Reactivity
Human
Applications
Western Blot
Purity
Immunogen Affinity Purified
Synonyms
SNAI3; Polyclonal Antibody; Anti-SNAI3 Antibody; Zinc finger protein SNAI3; MGC129606; Protein snail homolog 3; SMUC; SNAI3_ HUMAN; Snail homolog 3 (Drosophila); SNAIL3; Zfp293; Zinc finger protein 293; ZNF293; snail family zinc finger 3; anti-SNAI3 antibody
Reactivity
Human
Clonality
Polyclonal
Purity/Purification
Immunogen Affinity Purified
Form/Format
Lyophilized. Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Sequence Length
292
Applicable Applications for anti-SNAI3 antibody
Western Blot (WB)
Application Notes
Western Blot Concentration: 0.1-0.5ug/ml
Immunogen
A synthetic peptide corresponding to a sequence in the middle region of human SNAI3 (155-178aa FHCHKPYHTLAGLARHRQLHCHLQ), different from the related mouse sequence by two amino acids.
Ig Type
Rabbit IgG
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Preparation and Storage
At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquoted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.
Western Blot (WB)
(Anti- SNAI3 Picoband antibody, MBS177967, Western blottingAll lanes: Anti SNAI3 (MBS177967) at 0.5ug/mlWB: MCF-7 Whole Cell Lysate at 40ugPredicted bind size: 32KDObserved bind size: 32KD )
Western Blot (WB)
(Anti- SNAI3 Picoband antibody, MBS177967, Western blottingAll lanes: Anti SNAI3 (MBS177967) at 0.5ug/mlWB: MCF-7 Whole Cell Lysate at 40ugPredicted bind size: 32KDObserved bind size: 32KD )
Related Product Information for anti-SNAI3 antibody
Description: Rabbit IgG polyclonal antibody for Zinc finger protein SNAI3(SNAI3) detection. Tested with WB in Human.
Background: SNAI3 is a member of the SNAIL gene family, named for the Drosophila snail gene, which plays roles in mesodermal formation during embryogenesis. SNAI3 gene, was located between KIAA0233 gene and CBFA2T3 gene in human chromosome 16q24.3, a region affected in breast cancer, gastric cancer, hepatocellular carcinoma, ovarian cancer, and therapy-related myeloid leukemia with t(16;21)(q24;q22) translocation. Human SNAI3 gene was found to encode 292-amino-acid polypeptide with the N-terminal SNAG domain and five zinc finger domains. And Human SNAI3 mRNA was expressed in skin melanotic melanoma, lung epidermoid carcinoma, and germ cell tumor. Because SNAG zinc-finger proteins are transcriptional repressors implicated in carcinogenesis and embryogenesis, SNAI3 gene might be a potent target of pharmacogenomics in the field of oncology and regenerative medicine.
Background: SNAI3 is a member of the SNAIL gene family, named for the Drosophila snail gene, which plays roles in mesodermal formation during embryogenesis. SNAI3 gene, was located between KIAA0233 gene and CBFA2T3 gene in human chromosome 16q24.3, a region affected in breast cancer, gastric cancer, hepatocellular carcinoma, ovarian cancer, and therapy-related myeloid leukemia with t(16;21)(q24;q22) translocation. Human SNAI3 gene was found to encode 292-amino-acid polypeptide with the N-terminal SNAG domain and five zinc finger domains. And Human SNAI3 mRNA was expressed in skin melanotic melanoma, lung epidermoid carcinoma, and germ cell tumor. Because SNAG zinc-finger proteins are transcriptional repressors implicated in carcinogenesis and embryogenesis, SNAI3 gene might be a potent target of pharmacogenomics in the field of oncology and regenerative medicine.
References
1. Katoh M; Katoh M: Identification and characterization of human SNAIL3 (SNAI3) gene in silico. Int J Mol Med, 2003 Mar.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
32,474 Da
NCBI Official Full Name
zinc finger protein SNAI3
NCBI Official Synonym Full Names
snail family transcriptional repressor 3
NCBI Official Symbol
SNAI3
NCBI Official Synonym Symbols
SMUC; SNAIL3; ZNF293; Zfp293
NCBI Protein Information
zinc finger protein SNAI3
UniProt Protein Name
Zinc finger protein SNAI3
Protein Family
UniProt Gene Name
SNAI3
UniProt Synonym Gene Names
ZNF293
UniProt Entry Name
SNAI3_HUMAN
NCBI Description
SNAI3 is a member of the SNAIL gene family, named for the Drosophila snail gene, which plays roles in mesodermal formation during embryogenesis (Katoh and Katoh, 2003 [PubMed 12579345]).[supplied by OMIM, Apr 2009]
Uniprot Description
Snail3: Seems to inhibit myoblast differentiation. Transcriptional repressor of E-box-dependent transactivation of downstream myogenic bHLHs genes. Binds preferentially to the canonical E-box sequences 5'-CAGGTG-3' and 5'-CACCTG-3'. Belongs to the snail C2H2-type zinc-finger protein family.
Protein type: DNA-binding; C2H2-type zinc finger protein; Cell development/differentiation; Transcription factor
Chromosomal Location of Human Ortholog: 16q24.3
Cellular Component: nucleus; transcription factor complex
Molecular Function: copper ion binding
Biological Process: negative regulation of transcription from RNA polymerase II promoter; transcription, DNA-dependent
Research Articles on SNAI3
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Product Notes
The SNAI3 snai3 (Catalog #AAA177967) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The Anti-SNAI3 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's SNAI3 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Western Blot Concentration: 0.1-0.5ug/ml. Researchers should empirically determine the suitability of the SNAI3 snai3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SNAI3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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