Western Blot (WB)
(SMC1B Antibody (Center) western blot analysis in human normal Uterus tissue lysates (35ug/lane).This demonstrates the SMC1B antibody detected the SMC1B protein (arrow).)
Rabbit anti-Human SMC1B Polyclonal Antibody | anti-SMC1B antibody
SMC1B Antibody (Center)
Western Blot (WB)
(SMC1B Antibody (Center) western blot analysis in human normal Uterus tissue lysates (35ug/lane).This demonstrates the SMC1B antibody detected the SMC1B protein (arrow).)
Western Blot (WB)
(SMC1B Antibody (Center) western blot analysis in human normal Uterus tissue lysates (35ug/lane).This demonstrates the SMC1B antibody detected the SMC1B protein (arrow).)
Immunohistochemistry (IHC)
(SMC1B Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human colon tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of SMC1B Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)
Immunohistochemistry (IHC)
(SMC1B Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human colon tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of SMC1B Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)
NCBI and Uniprot Product Information
NCBI Description
SMC1L2 belongs to a family of proteins required for chromatid cohesion and DNA recombination during meiosis and mitosis (3:Revenkova et al., 2001 [PubMed 11564881]).[supplied by OMIM, Mar 2008]
Uniprot Description
SMC1B: Meiosis-specific component of cohesin complex. Required for the maintenance of meiotic cohesion, but not, or only to a minor extent, for its establishment. Contributes to axial element (AE) formation and the organization of chromatin loops along the AE. Plays a key role in synapsis, recombination and chromosome movements. The cohesin complex is required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. The meiosis-specific cohesin complex probably replaces mitosis specific cohesin complex when it dissociates from chromatin during prophase I. Belongs to the SMC family. SMC1 subfamily. 3 isoforms of the human protein are produced by alternative splicing.
Chromosomal Location of Human Ortholog: 22q13.31
Cellular Component: nucleoplasm; lateral element; cytoplasm; chromosome, pericentric region
Molecular Function: DNA binding; ATP binding
Biological Process: meiosis; sister chromatid cohesion
Research Articles on SMC1B
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Product Notes
The SMC1B smc1b (Catalog #AAA9208358) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 737-765. The SMC1B Antibody (Center) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's SMC1B can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC). WB~~1:1000. Researchers should empirically determine the suitability of the SMC1B smc1b for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SMC1B, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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