Western Blot (WB)
(Gel: 12%SDS-PAGE, Lysate: 40 ug, Lane 1-3: Mouse thymus tissue, PC-3 and 293T cell, Primary antibody: 123903(GINS4 Antibody) at dilution 1/350, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 40 seconds)
Rabbit anti-Human, Mouse SLD5 Polyclonal Antibody | anti-SLD5 antibody
SLD5 Rabbit pAb
Western Blot (WB)
(Gel: 12%SDS-PAGE, Lysate: 40 ug, Lane 1-3: Mouse thymus tissue, PC-3 and 293T cell, Primary antibody: 123903(GINS4 Antibody) at dilution 1/350, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 40 seconds)
Western Blot (WB)
(Gel: 12%SDS-PAGE, Lysate: 40 ug, Lane 1-3: Mouse thymus tissue, PC-3 and 293T cell, Primary antibody: 123903(GINS4 Antibody) at dilution 1/350, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 40 seconds)
Immunohistochemistry (IHC)
(The image is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using 123903(GINS4 Antibody) at dilution 1/30. (Original magnification: ×200))
Immunohistochemistry (IHC)
(The image is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using 123903(GINS4 Antibody) at dilution 1/30. (Original magnification: ×200))
Immunohistochemistry (IHC)
(The image is immunohistochemistry of paraffin-embedded Human breast cancer tissue using 123903(GINS4 Antibody) at dilution 1/30. (Original magnification: ×200))
Immunohistochemistry (IHC)
(The image is immunohistochemistry of paraffin-embedded Human breast cancer tissue using 123903(GINS4 Antibody) at dilution 1/30. (Original magnification: ×200))
NCBI and Uniprot Product Information
NCBI Description
The yeast heterotetrameric GINS complex is made up of Sld5, Psf1 (GINS1; MIM 610608), Psf2 (GINS2; MIM 610609), and Psf3 (GINS3; MIM 610610). The formation of the GINS complex is essential for the initiation of DNA replication in yeast and Xenopus egg extracts (Ueno et al., 2005 [PubMed 16287864]). See GINS1 for additional information about the GINS complex.[supplied by OMIM, Mar 2008]
Uniprot Description
GINS4: The GINS complex plays an essential role in the initiation of DNA replication, and progression of DNA replication forks. GINS4 is important for GINS complex assembly. GINS complex seems to bind preferentially to single-stranded DNA. Belongs to the GINS4/SLD5 family. 2 isoforms of the human protein are produced by alternative splicing.
Chromosomal Location of Human Ortholog: 8p11.21
Cellular Component: nucleoplasm; cytoplasm
Molecular Function: protein binding
Biological Process: mitotic cell cycle; DNA strand elongation during DNA replication; inner cell mass cell proliferation
Research Articles on SLD5
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Product Notes
The SLD5 gins4 (Catalog #AAA4754564) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The SLD5 Rabbit pAb reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's SLD5 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry-Paraffin (IHC-P). WB: 1:200-1:1000. Researchers should empirically determine the suitability of the SLD5 gins4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SLD5, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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