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Western Blot (WB) (Western blot analysis of extracts from HepG2 cells, MCF-7 cells and HeLa cells, using SLCO1A2 antibody.)

Rabbit anti-Human SLCO1A2 Polyclonal Antibody | anti-SLCO1A2 antibody

SLCO1A2 Antibody

Gene Names
SLCO1A2; OATP; OATP-A; OATP1A2; SLC21A3
Reactivity
Human
Applications
Western Blot
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Synonyms
SLCO1A2; Polyclonal Antibody; SLCO1A2 Antibody; OATP; OATP-A; OATP1; OATP1A2; organic anion transporting polypeptide A; anti-SLCO1A2 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Specificity
The antibody detects endogenous levels of total SLCO1A2 protein.
Purity/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form/Format
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1.0 mg/ml (varies by lot)
Sequence Length
670
Applicable Applications for anti-SLCO1A2 antibody
Western Blot (WB)
Application Notes
Western blotting: 1:500~1:3000
Immunogen Type
Peptide
Immunogen Description
Synthesized peptide derived from internal of human SLCO1A2.
Target Name
SLCO1A2
Preparation and Storage
Store at -20 degree C

Western Blot (WB)

(Western blot analysis of extracts from HepG2 cells, MCF-7 cells and HeLa cells, using SLCO1A2 antibody.)

Western Blot (WB) (Western blot analysis of extracts from HepG2 cells, MCF-7 cells and HeLa cells, using SLCO1A2 antibody.)
Related Product Information for anti-SLCO1A2 antibody
Mediates the Na+-independent transport of organic anions such as sulfobromophthalein (BSP) and conjugated (taurocholate) and unconjugated (cholate) bile acids By similarity. Selectively inhibited by the grapefruit juice component naringin.Kullak-Ublick G.-A., Gastroenterology 109:1274-1282(1995).Koenig J., J. Biol. Chem. 275:23161-23168(2000).Lee W., J. Biol. Chem. 280:9610-9617(2005).
Product Categories/Family for anti-SLCO1A2 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
64,369 Da
NCBI Official Full Name
solute carrier organic anion transporter family member 1A2
NCBI Official Synonym Full Names
solute carrier organic anion transporter family, member 1A2
NCBI Official Symbol
SLCO1A2
NCBI Official Synonym Symbols
OATP; OATP-A; OATP1A2; SLC21A3
NCBI Protein Information
solute carrier organic anion transporter family member 1A2
UniProt Protein Name
Solute carrier organic anion transporter family member 1A2
UniProt Gene Name
SLCO1A2
UniProt Synonym Gene Names
OATP; OATP1; OATP1A2; SLC21A3; OATP-1
UniProt Entry Name
SO1A2_HUMAN

NCBI Description

This gene encodes a sodium-independent transporter which mediates cellular uptake of organic ions in the liver. Its substrates include bile acids, bromosulphophthalein, and some steroidal compounds. The protein is a member of the SLC21A family of solute carriers. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Dec 2008]

Uniprot Description

SLCO1A2: Mediates the Na(+)-independent transport of organic anions such as sulfobromophthalein (BSP) and conjugated (taurocholate) and unconjugated (cholate) bile acids. Selectively inhibited by the grapefruit juice component naringin. Belongs to the organo anion transporter (TC 2.A.60) family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Transporter, SLC family; Transporter; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 12p12

Cellular Component: integral to membrane; plasma membrane

Molecular Function: organic anion transmembrane transporter activity

Biological Process: bile acid and bile salt transport; sodium-independent organic anion transport; bile acid metabolic process; transmembrane transport; organic anion transport

Research Articles on SLCO1A2

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Product Notes

The SLCO1A2 slco1a2 (Catalog #AAA9403805) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The SLCO1A2 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's SLCO1A2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Western blotting: 1:500~1:3000. Researchers should empirically determine the suitability of the SLCO1A2 slco1a2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SLCO1A2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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