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Immunohistochemistry (IHC) (Anti-SLC7A2 antibody IHC of human stomach. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)

Rabbit SLC7A2 Polyclonal Antibody | anti-SLC7A2 antibody

Rabbit Polyclonal to Human SLC7A2

Gene Names
SLC7A2; CAT2; ATRC2; HCAT2
Reactivity
Chimpanzee, Gorilla, Human, Mouse, Pig, Rabbit, Rat
Predicted Reactivity: Orangutan, Gibbon, Monkey, Bat, Bovine, Hamster, Horse (at least 90% immunogen sequence identity)
Applications
Immunohistochemistry
Purity
Immunoaffinity Purified
Synonyms
SLC7A2; Polyclonal Antibody; Rabbit Polyclonal to Human SLC7A2; Anti-SLC7A2 Antibody (Internal) IHC-plus; ATRC2; CAT2; HCAT2; CAT-2; Human SLC7A2; anti-SLC7A2 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Chimpanzee, Gorilla, Human, Mouse, Pig, Rabbit, Rat
Predicted Reactivity: Orangutan, Gibbon, Monkey, Bat, Bovine, Hamster, Horse (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Specificity
Human SLC7A2. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except TPR (67%).
Purity/Purification
Immunoaffinity Purified
Form/Format
PBS, 0.1% sodium azide.
Concentration
1 mg/ml (varies by lot)
Sequence Length
658
Applicable Applications for anti-SLC7A2 antibody
Immunohistochemistry (IHC - Paraffin)
Application Notes
IHC-P (15 ug/ml)
Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti...
Target Species
Human
Immunogen Description
Synthetic 12 amino acid peptide from internal region of human SLC7A2.
Immunogen Type
Synthetic peptide
Immunogen
SLC7A2 antibody was raised against synthetic 12 amino acid peptide from internal region of human SLC7A2. Percent identity with other species by BLAST analysis: Human, Chimpanzee, Gorilla, Monkey, Mouse, Rat, Rabbit, Pig (100%); Orangutan, Gibbon, Galago, Marmoset, Hamster, Bovine, Bat, Horse (92%); Panda, Dog, Platypus (83%).
Antigen Modification
Internal
Preparation and Storage
Long term: -70 degree C; Short term: +4 degree C

Immunohistochemistry (IHC)

(Anti-SLC7A2 antibody IHC of human stomach. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)

Immunohistochemistry (IHC) (Anti-SLC7A2 antibody IHC of human stomach. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)

Immunohistochemistry (IHC)

(Anti-SLC7A2 antibody IHC of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)

Immunohistochemistry (IHC) (Anti-SLC7A2 antibody IHC of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)
Related Product Information for anti-SLC7A2 antibody
Solute Carrier Family 7, Member 2, (SLC7A2) also known as Cationic Amino Acid Transporter 2 (hCAT2)mediates the transport of the cationic amino acids arginine, lysine and ornithine and is a member of the APC family of transporters. The transport characteristics of hCAT2 are consistent with those of the y+ system which is involved in susceptibility to murine ecotropic retroviruses.
Product Categories/Family for anti-SLC7A2 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
75,986 Da
NCBI Official Full Name
cationic amino acid transporter 2 isoform 2
NCBI Official Synonym Full Names
solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
NCBI Official Symbol
SLC7A2
NCBI Official Synonym Symbols
CAT2; ATRC2; HCAT2
NCBI Protein Information
cationic amino acid transporter 2; low affinity cationic amino acid transporter 2
UniProt Protein Name
Cationic amino acid transporter 2
UniProt Gene Name
SLC7A2
UniProt Synonym Gene Names
ATRC2; CAT2; CAT-2; CAT2
UniProt Entry Name
CTR2_HUMAN

NCBI Description

The protein encoded by this gene is a cationic amino acid transporter and a member of the APC (amino acid-polyamine-organocation) family of transporters. The encoded membrane protein is responsible for the cellular uptake of arginine, lysine and ornithine. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]

Uniprot Description

SLC7A2: Low-affinity, high capacity permease involved in the transport of the cationic amino acids (arginine, lysine and ornithine). Plays a regulatory role in classical or alternative activation of macrophages. Belongs to the amino acid-polyamine-organocation (APC) superfamily. Cationic amino acid transporter (CAT) (TC 2.A.3.3) family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, multi-pass; Transporter, SLC family; Transporter; Membrane protein, integral

Chromosomal Location of Human Ortholog: 8p22

Cellular Component: membrane; integral to plasma membrane; plasma membrane

Molecular Function: high affinity arginine transmembrane transporter activity; high affinity lysine transmembrane transporter activity; basic amino acid transmembrane transporter activity

Biological Process: amino acid metabolic process; macrophage activation; amino acid transport; transport; regulation of macrophage activation; regulation of inflammatory response; production of nitric oxide during acute inflammatory response; ion transport; nitric oxide biosynthetic process; transmembrane transport

Research Articles on SLC7A2

Similar Products

Product Notes

The SLC7A2 slc7a2 (Catalog #AAA244168) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit Polyclonal to Human SLC7A2 reacts with Chimpanzee, Gorilla, Human, Mouse, Pig, Rabbit, Rat Predicted Reactivity: Orangutan, Gibbon, Monkey, Bat, Bovine, Hamster, Horse (at least 90% immunogen sequence identity) and may cross-react with other species as described in the data sheet. AAA Biotech's SLC7A2 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC - Paraffin). IHC-P (15 ug/ml) Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti.. Researchers should empirically determine the suitability of the SLC7A2 slc7a2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SLC7A2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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