Rabbit anti-Human, Mouse SLC6A13 Polyclonal Antibody | anti-SLC6A13 antibody

SLC6A13 Antibody

Cat. Num. AAA7053337

• Gene Names: SLC6A13; GAT2; GAT3; GAT-2
• Reactivity: Human, Mouse
• Applications: ELISA, Western Blot, Immunohistochemistry, Immunofluorescence
• Purity: >95%, Protein G purified
• Synonyms: SLC6A13; Polyclonal Antibody; SLC6A13 Antibody; Sodium- and chloride-dependent GABA transporter 2; GAT-2; Solute carrier family 6 member 13; GAT2; anti-SLC6A13 antibody

• Host: Rabbit
• Reactivity: Human, Mouse
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: >95%, Protein G purified
• Form/Format: Liquid
• Sequence Length: 510

• Applicable Applications for anti-SLC6A13 antibody: ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
• Application Notes: WB: 1:500-1:5000; IHC: 1:20-1:200; IF: 1:50-1:200
• Immunogen: Recombinant Human Sodium- and chloride-dependent GABA transporter 2 protein (1-40AA)
• Conjugation: Non-conjugated
• Preservative: 0.03% Proclin 300
• Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
• Preparation and Storage: Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.

Western Blot (WB)

(Western BlotPositive WB detected in: Mouse heart tissue,Mouse brain tissue,Mouse kidney tissueAll lanes: SLC6A13 antibody at 3ug/mlSecondaryGoat polyclonal to rabbit IgG at 1/50000 dilutionPredicted band size: 69,58,11 KDaObserved band size: 69 KDa)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human testis tissue using MBS7053337 at dilution of 1:100)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human kidney tissue using MBS7053337 at dilution of 1:100)

Immunofluorescence (IF)

(Immunofluorescent analysis of A549 cells using MBS7053337 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L))

Related Product Information for anti-SLC6A13 antibody

Sodium-dependent GABA and taurine transporter. In presynaptic terminals, regulates GABA signaling termination through GABA uptake. May also be involved in beta-alanine transport.

NCBI and Uniprot Product Information

• NCBI GI #: 300360519
• NCBI GeneID: 6540
• NCBI Accession #: NP_001177926.1
• NCBI GenBank Nucleotide #: NM_001190997.2
• UniProt Accession #: Q9NSD5; Q8TCC2; Q8WW56; B4DJL1
• Molecular Weight: 10,910 Da
• NCBI Official Full Name: sodium- and chloride-dependent GABA transporter 2 isoform 2
• NCBI Official Synonym Full Names: solute carrier family 6 member 13
• NCBI Official Symbol: SLC6A13
• NCBI Official Synonym Symbols: GAT2; GAT3; GAT-2
• NCBI Protein Information: sodium- and chloride-dependent GABA transporter 2
• UniProt Protein Name: Sodium- and chloride-dependent GABA transporter 2
• Protein Family: Sodium- and chloride-dependent GABA transporter
• UniProt Gene Name: SLC6A13
• UniProt Synonym Gene Names: GAT2; GAT-2

Uniprot Description

SLC6A13: Terminates the action of GABA by its high affinity sodium-dependent reuptake into presynaptic terminals. Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A13 subfamily. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Membrane protein, multi-pass; Transporter; Transporter, SLC family

Chromosomal Location of Human Ortholog: 12p13.33

Cellular Component: integral to plasma membrane; neuron projection; plasma membrane

Molecular Function: gamma-aminobutyric acid:sodium symporter activity

Biological Process: gamma-aminobutyric acid transport; neurotransmitter transport; synaptic transmission