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Western Blot (WB) (Western blot analysis of 1) Mouse Brain Tissue, 2)Rat Brain Tissue with GABA Transporter 1 Rabbit pAb diluted at 1:2,000.)

Rabbit SLC6A1 Polyclonal Antibody | anti-SLC6A1 antibody

SLC6A1 Antibody

Gene Names
SLC6A1; GAT1; GABATR; GABATHG
Reactivity
Human, Mouse, Rat
Applications
Western Blot, ELISA, Immunohistochemistry
Purity
Affinity-purified from rabbit antiserum by affinity-chromatography using specific immunogen.
Synonyms
SLC6A1; Polyclonal Antibody; SLC6A1 Antibody; GABATR; GABT1; GAT1; Sodium- and chloride-dependent GABA Transporter 1; GAT-1; Solute carrier family 6 member 1; anti-SLC6A1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using specific immunogen.
Form/Format
Liquid; In Phosphate Buffered Saline, 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Applicable Applications for anti-SLC6A1 antibody
Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC) Paraffin
Application Notes
WB: 1:1000-2000
IHC-P: 1:100-200
Immunogen
Synthetic Peptide
Immunogen Species
Human
Conjugate
Non-conjugated
Preparation and Storage
Upon receipt, store at -20 degree C or -80 degree C. Avoid repeated freeze.

Western Blot (WB)

(Western blot analysis of 1) Mouse Brain Tissue, 2)Rat Brain Tissue with GABA Transporter 1 Rabbit pAb diluted at 1:2,000.)

Western Blot (WB) (Western blot analysis of 1) Mouse Brain Tissue, 2)Rat Brain Tissue with GABA Transporter 1 Rabbit pAb diluted at 1:2,000.)

Immunohistochemistry (IHC)

(Immunohistochemical analysis of paraffin-embedded Rat BrainTissue using GABA Transporter 1 Rabbit pAb diluted at 1:200.)

Immunohistochemistry (IHC) (Immunohistochemical analysis of paraffin-embedded Rat BrainTissue using GABA Transporter 1 Rabbit pAb diluted at 1:200.)

Immunohistochemistry (IHC)

(Immunohistochemical analysis of paraffin-embedded Mouse BrainTissue using GABA Transporter 1 Rabbit pAb diluted at 1:200.)

Immunohistochemistry (IHC) (Immunohistochemical analysis of paraffin-embedded Mouse BrainTissue using GABA Transporter 1 Rabbit pAb diluted at 1:200.)
Product Categories/Family for anti-SLC6A1 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
67,074 Da
NCBI Official Full Name
sodium- and chloride-dependent GABA transporter 1
NCBI Official Synonym Full Names
solute carrier family 6 (neurotransmitter transporter, GABA), member 1
NCBI Official Symbol
SLC6A1
NCBI Official Synonym Symbols
GAT1; GABATR; GABATHG
NCBI Protein Information
sodium- and chloride-dependent GABA transporter 1; GAT-1; solute carrier family 6 member 1
UniProt Protein Name
Sodium- and chloride-dependent GABA transporter 1
UniProt Gene Name
SLC6A1
UniProt Synonym Gene Names
GABATR; GABT1; GAT1; GAT-1
UniProt Entry Name
SC6A1_HUMAN

NCBI Description

The SLC6A1 gene encodes a gamma-aminobutyric acid (GABA) transporter, which removes GABA from the synaptic cleft (Hirunsatit et al., 2009 [PubMed 19077666]).[supplied by OMIM, Jul 2009]

Uniprot Description

SLC6A1: Terminates the action of GABA by its high affinity sodium-dependent reuptake into presynaptic terminals. Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A1 subfamily.

Protein type: Membrane protein, multi-pass; Transporter; Transporter, SLC family; Membrane protein, integral

Chromosomal Location of Human Ortholog: 3p25.3

Cellular Component: cell surface; membrane; integral to plasma membrane; axon; plasma membrane; integral to membrane

Molecular Function: gamma-aminobutyric acid:sodium symporter activity; neurotransmitter:sodium symporter activity

Biological Process: response to purine; response to toxin; neurotransmitter secretion; learning; response to cocaine; response to estradiol stimulus; response to sucrose stimulus; synaptic transmission; transport; response to lead ion; gamma-aminobutyric acid import; negative regulation of synaptic transmission, GABAergic; response to calcium ion; transmembrane transport; protein homooligomerization; positive regulation of gamma-aminobutyric acid secretion

Disease: Myoclonic-atonic Epilepsy

Research Articles on SLC6A1

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Product Notes

The SLC6A1 slc6a1 (Catalog #AAA7122707) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The SLC6A1 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's SLC6A1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC) Paraffin. WB: 1:1000-2000 IHC-P: 1:100-200. Researchers should empirically determine the suitability of the SLC6A1 slc6a1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SLC6A1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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