Immunohistochemistry (IHC)
(Anti-SLC47A1 / MATE1 antibody IHC staining of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)
Rabbit anti-Human SLC47A1 / MATE1 Polyclonal Antibody | anti-SLC47A1 / MATE1 antibody
Anti-SLC47A1 / MATE1 Antibody (aa 492-519) IHC-plus
WB (1:1000)
For long term storage store at -20 degree C.
Immunohistochemistry (IHC)
(Anti-SLC47A1 / MATE1 antibody IHC staining of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)
Immunohistochemistry (IHC)
(Anti-SLC47A1 / MATE1 antibody IHC staining of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)
Western Blot (WB)
(SLC47A1 Antibody western blot of HepG2(lane 1),MDA-MB435(lane 2) cell line lysates (35 ug/lane). The SLC47A1 antibody detected the SLC47A1 protein (arrow).)
Western Blot (WB)
(SLC47A1 Antibody western blot of HepG2(lane 1),MDA-MB435(lane 2) cell line lysates (35 ug/lane). The SLC47A1 antibody detected the SLC47A1 protein (arrow).)
NCBI and Uniprot Product Information
NCBI Description
This gene is located within the Smith-Magenis syndrome region on chromosome 17. It encodes a protein of unknown function. [provided by RefSeq, Jul 2008]
Uniprot Description
SLC47A1: Solute transporter for tetraethylammonium (TEA), 1- methyl-4-phenylpyridinium (MPP), cimetidine, N-methylnicotinamide (NMN), metformin, creatinine, guanidine, procainamide, topotecan, estrone sulfate, acyclovir, ganciclovir and also the zwitterionic cephalosporin, cephalexin and cephradin. Seems to also play a role in the uptake of oxaliplatin (a new platinum anticancer agent). Able to transport paraquat (PQ or N,N-dimethyl-4-4'-bipiridinium); a widely used herbicid. Responsible for the secretion of cationic drugs across the brush border membranes. Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, multi-pass; Transporter, SLC family; Membrane protein, integral; Transporter
Chromosomal Location of Human Ortholog: 17p11.2
Cellular Component: integral to membrane; plasma membrane
Molecular Function: drug transporter activity; monovalent cation:proton antiporter activity
Biological Process: multidrug transport; organic cation transport; transmembrane transport
Research Articles on SLC47A1 / MATE1
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Product Notes
The SLC47A1 / MATE1 slc47a1 (Catalog #AAA249572) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-SLC47A1 / MATE1 Antibody (aa 492-519) IHC-plus reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's SLC47A1 / MATE1 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC) Paraffin, Western Blot (WB). IHC-P (1:10 - 1:100) WB (1:1000). Researchers should empirically determine the suitability of the SLC47A1 / MATE1 slc47a1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SLC47A1 / MATE1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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