Western Blot (WB)
(Western Blot analysis of SLC27A1 expression in mouse lung usingMBS629720.)
Rabbit anti-Human, Mouse SLC27A1 Polyclonal Antibody | anti-SLC27A1 antibody
SLC27A1 (Long-chain Fatty Acid Transport Protein 1, FATP-1, Fatty Acid Transport Protein 1, Solute Carrier Family 27 Member 1ACSVL5, FATP1) APC
Western Blot (WB)
(Western Blot analysis of SLC27A1 expression in mouse lung usingMBS629720.)
Western Blot (WB)
(Western Blot analysis of SLC27A1 expression in mouse lung usingMBS629720.)
Western Blot (WB)
(Western Blot analysis of SLC27A1 expression in transfected 293T cell line usingMBS629720. Lane 1: SLC27A1 transfected lysate (71.10kD). Lane 2: Non-transfected lysate.)
Western Blot (WB)
(Western Blot analysis of SLC27A1 expression in transfected 293T cell line usingMBS629720. Lane 1: SLC27A1 transfected lysate (71.10kD). Lane 2: Non-transfected lysate.)
NCBI and Uniprot Product Information
Uniprot Description
SLC27A1: Involved in translocation of long-chain fatty acids (LFCA) across the plasma membrane. The LFCA import appears to be hormone-regulated in a tissue-specific manner. In adipocytes, but not myocytes, insulin induces a rapid translocation of FATP1 from intracellular compartments to the plasma membrane, paralleled by increased LFCA uptake. May act directly as a bona fide transporter, or alternatively, in a cytoplasmic or membrane- associated multimeric protein complex to trap and draw fatty acids towards accumulation. Plays a pivotal role in regulating available LFCA substrates from exogenous sources in tissues undergoing high levels of beta-oxidation or triglyceride synthesis. May be involved in regulation of cholesterol metabolism. Has acyl-CoA ligase activity for long-chain and very-long-chain fatty acids. Belongs to the ATP-dependent AMP-binding enzyme family.
Protein type: EC 6.2.1.-; Ligase; Lipid-binding; Membrane protein, integral; Mitochondrial; Vesicle
Chromosomal Location of Human Ortholog: 19p13.11
Cellular Component: endoplasmic reticulum; integral component of membrane; membrane; plasma membrane
Molecular Function: fatty acid transmembrane transporter activity; long-chain-fatty-acid-CoA ligase activity; nucleotide binding; protein homodimerization activity; very long-chain fatty acid-CoA ligase activity
Biological Process: adiponectin-activated signaling pathway; cardiolipin biosynthetic process; long-chain fatty acid metabolic process; long-chain fatty acid transport; medium-chain fatty acid transport; phosphatidic acid biosynthetic process; phosphatidylcholine biosynthetic process; phosphatidylethanolamine biosynthetic process; phosphatidylglycerol biosynthetic process; phosphatidylinositol biosynthetic process; phosphatidylserine biosynthetic process; positive regulation of heat generation; regulation of lipid metabolic process; response to cold; response to insulin stimulus
Research Articles on SLC27A1
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Product Notes
The SLC27A1 slc27a1 (Catalog #AAA6500305) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The SLC27A1 (Long-chain Fatty Acid Transport Protein 1, FATP-1, Fatty Acid Transport Protein 1, Solute Carrier Family 27 Member 1ACSVL5, FATP1) APC reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's SLC27A1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the SLC27A1 slc27a1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SLC27A1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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