Rabbit anti-Mouse SLC25A20 Polyclonal Antibody | anti-SLC25A20 antibody

SLC25A20, CT (SLC25A20, CAC, CACT, Mitochondrial carnitine/acylcarnitine carrier protein, Carnitine/acylcarnitine translocase, Solute carrier family 25 member 20) (Biotin)

Cat. Num. AAA6348244

• Gene Names: SLC25A20; CAC; CACT
• Reactivity: Mouse
• Applications: Western Blot, ELISA
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: SLC25A20; Polyclonal Antibody; CT (SLC25A20; CAC; CACT; Mitochondrial carnitine/acylcarnitine carrier protein; Carnitine/acylcarnitine translocase; Solute carrier family 25 member 20) (Biotin); mitochondrial carnitine/acylcarnitine carrier protein; Solute carrier family 25 member 20; anti-SLC25A20 antibody

• Host: Rabbit
• Reactivity: Mouse
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Biotin.

• Applicable Applications for anti-SLC25A20 antibody: Western Blot (WB), ELISA (EIA)
• Application Notes: WB: 1:100-500; ELISA: 1:1,000; Applications are based on unconjugated antibody.
• Immunogen: SLC25A20 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 234-264 amino acids from the C-terminal region of human SLC25A20.
• Conjugate: Biotin
• Note: Preservative Free
• Preparation and Storage: Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(SLC25A20 Antibody (C-term) western blot analysis in mouse cerebellum tissue lysates (35ug/lane).This demonstrates the SLC25A20 antibody detected the SLC25A20 protein (arrow).)

Related Product Information for anti-SLC25A20 antibody

This gene product is one of several closely related mitochondrial-membrane carrier proteins that shuttle substrates between cytosol and the intramitochondrial matrix space. This protein mediates the transport of acylcarnitines into mitochondrial matrix for their oxidation by the mitochondrial fatty acid-oxidation pathway. Mutations in this gene are associated with carnitine-acylcarnitine translocase deficiency, which can cause a variety of pathological conditions such as hypoglycemia, cardiac arrest, hepatomegaly, hepatic dysfunction and muscle weakness, and is usually lethal in new born and infants.

Product Categories/Family for anti-SLC25A20 antibody

Antibodies; Mitochondrial Proteins

References

Tachibana, K., et al. Biochem. Biophys. Res. Commun. 389(3):501-505(2009). De Lucas, J.R., et al. Mol. Membr. Biol. 25(2):152-163(2008). Pierre, G., et al. J. Inherit. Metab. Dis. 30 (5), 815 (2007): Peluso, G., et al. J. Cell. Physiol. 203(2):439-446(2005). Kahn, B.B., et al. Cell Metab. 1(1):15-25(2005).

NCBI and Uniprot Product Information

• NCBI GI #: 4557403
• NCBI GeneID: 788
• NCBI Accession #: NP_000378.1
• NCBI GenBank Nucleotide #: NM_000387.5
• UniProt Accession #: O43772; Q9UIQ2; B2R7F4
• Molecular Weight: 32,944 Da
• NCBI Official Full Name: mitochondrial carnitine/acylcarnitine carrier protein
• NCBI Official Synonym Full Names: solute carrier family 25 (carnitine/acylcarnitine translocase), member 20
• NCBI Official Symbol: SLC25A20
• NCBI Official Synonym Symbols: CAC; CACT
• NCBI Protein Information: mitochondrial carnitine/acylcarnitine carrier protein
• UniProt Protein Name: Mitochondrial carnitine/acylcarnitine carrier protein
• Protein Family: Mitochondrial carnitine/acylcarnitine carrier protein
• UniProt Gene Name: SLC25A20
• UniProt Synonym Gene Names: CAC; CACT; CAC
• UniProt Entry Name: MCAT_HUMAN

NCBI Description

This gene product is one of several closely related mitochondrial-membrane carrier proteins that shuttle substrates between cytosol and the intramitochondrial matrix space. This protein mediates the transport of acylcarnitines into mitochondrial matrix for their oxidation by the mitochondrial fatty acid-oxidation pathway. Mutations in this gene are associated with carnitine-acylcarnitine translocase deficiency, which can cause a variety of pathological conditions such as hypoglycemia, cardiac arrest, hepatomegaly, hepatic dysfunction and muscle weakness, and is usually lethal in new born and infants. [provided by RefSeq, Jul 2008]

Uniprot Description

Function: Mediates the transport of acylcarnitines of different length across the mitochondrial inner membrane from the cytosol to the mitochondrial matrix for their oxidation by the mitochondrial fatty acid-oxidation pathway.