Western Blot (WB)
(Anti-SLC22A7 antibody, MBS177093, Western blottingLane 1: Rat Liver Tissue LysateLane 2: Human Placenta Tissue LysateLane 3: 293T Cell LysateLane 4: SMMC Cell Lysate )
Rabbit SLC22A7 Polyclonal Antibody | anti-SLC22A7 antibody
Anti-SLC22A7 antibody
Predicted to work with: Mouse
Predicted to work with: Mouse
Tested Species: In house tested species with positive results.
Predicted Species: Species is predicted to be fit for the product based on sequence similarities.
Other applications have not been tested.
Optimal dilutions should be determined by the end user.
Antibody can be supported by chemiluminescence kit MBS176460 in Western Blot.
Western Blot (WB)
(Anti-SLC22A7 antibody, MBS177093, Western blottingLane 1: Rat Liver Tissue LysateLane 2: Human Placenta Tissue LysateLane 3: 293T Cell LysateLane 4: SMMC Cell Lysate )
Western Blot (WB)
(Anti-SLC22A7 antibody, MBS177093, Western blottingLane 1: Rat Liver Tissue LysateLane 2: Human Placenta Tissue LysateLane 3: 293T Cell LysateLane 4: SMMC Cell Lysate )
Background: Solute carrier family 22 member 7, also called SLC22A7 or OAT2 is a protein that in humans is encoded by the SLC22A7 gene. This gene is mapped to 6p21.1. The protein encoded by this gene is involved in the sodium-independent transport and excretion of organic anions, some of which are potentially toxic. The encoded protein is an integral membrane protein and appears to be localized to the basolateral membrane of the kidney. This gene transports prostaglandin E2, prostaglandin F2, tetracycline, bumetanide, estrone sulfate, glutarate, dehydroepiandrosterone sulfate, allopurinol, 5-fluorouracil, paclitaxel, L-ascorbic acid, salicylate, ethotrexate, and alpha-ketoglutarate.
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is involved in the sodium-independent transport and excretion of organic anions, some of which are potentially toxic. The encoded protein is an integral membrane protein and appears to be localized to the basolateral membrane of the kidney. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
Uniprot Description
SLC22A7: Mediates sodium-independent multispecific organic anion transport. Transport of prostaglandin E2, prostaglandin F2, tetracycline, bumetanide, estrone sulfate, glutarate, dehydroepiandrosterone sulfate, allopurinol, 5-fluorouracil, paclitaxel, L-ascorbic acid, salicylate, ethotrexate, and alpha- ketoglutarate. Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family. 4 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, multi-pass; Membrane protein, integral; Transporter, SLC family; Transporter
Chromosomal Location of Human Ortholog: 6p21.1
Cellular Component: membrane; basolateral plasma membrane; integral to plasma membrane; plasma membrane
Molecular Function: sodium-independent organic anion transmembrane transporter activity
Biological Process: transmembrane transport; organic anion transport
Research Articles on SLC22A7
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Product Notes
The SLC22A7 slc22a7 (Catalog #AAA177093) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-SLC22A7 antibody reacts with Reacts with: Human, Rat Predicted to work with: Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's SLC22A7 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: Concentration: 0.1-0.5ug/ml; Tested Species : Human, Rat; Predicted Species: Mouse Tested Species: In house tested species with positive results. Predicted Species: Species is predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by the end user. Antibody can be supported by chemiluminescence kit MBS176460 in Western Blot. Researchers should empirically determine the suitability of the SLC22A7 slc22a7 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SLC22A7, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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