Rabbit SIN4 Polyclonal Antibody | anti-SIN4 antibody

Rabbit anti-Saccharomyces cerevisiae (strain ATCC 204508/S288c)(Baker's yeast) SIN4 Polyclonal Antibody

• Gene Names: SIN4; BEL2; GAL22; MED16; RYE1; SDI3; SSF5; SSN4; SSX3; TSF3
• Reactivity: Saccharomyces cerevisiae (strain ATCC 204508/S288c)(Baker's yeast)
• Applications: ELISA, Western Blot
• Purity: Protein A/G
• Synonyms: SIN4; Polyclonal Antibody; Rabbit anti-Saccharomyces cerevisiae (strain ATCC 204508/S288c)(Baker's yeast) SIN4 Polyclonal Antibody; SIN4 Antibody; Mediator of RNA polymerase II transcription subunit 16; Global transcriptional regulator SIN4; Mediator complex subunit 16; SNF1 suppressor protein 4; SWI4 suppressor protein 5; Transcriptional silencing factor 3; YGP1 expression regulatory protein 1; SIN4 BEL2 GAL22 MED16 RYE1 SDI3 SSF5 SSN4 TSF3 YNL236W N1135; anti-SIN4 antibody

• Host: Rabbit
• Reactivity: Saccharomyces cerevisiae (strain ATCC 204508/S288c)(Baker's yeast)
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Protein A/G
• Form/Format: Liquid; Preservative: 0.03% Proclin 300; Constituents: 50% Glycerol, 0.01M PBS, pH7.4

• Applicable Applications for anti-SIN4 antibody: ELISA (EIA), WB (Western Blot) (ensure identification of antigen)
• Immunogen: Recombinant Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) SIN4 protein
• Conjugation: Non-conjugate
• Modification: Unmodified
• Deliverables: 1. 200ug recombinant immunogen protein/peptide (positive control).; 2. 1mL preimmune serum (negative control); 3. 10mg rabbit polyclonal antibody purified by Protein A/G.
• Quality Guarantee: 1. Antibody purity >90% confirmed by SDS-PAGE.; 2. Antibody titer > 1: 64,000 confirmed by ELISA; 3. Western Blot positive for the immunogen protein (Not applicable for synthetic peptide).
• Complementary Antibody: Customer can choose 1 FREE antibody from the list below. Please specify the catalog # when order:; * 6*His Monoclonal Antibody #MBS1491670; * DYKDDDDK tag Monoclonal Antibody #MBS1493946; * GAPDH Monoclonal Antibody #MBS1495524; * GFP Monoclonal Antibody #MBS1496050; * Myc tag Monoclonal Antibody #MBS1497694; * GST Monoclonal Antibody #MBS1497871; * Sumo tag Monoclonal Antibody #MBS1498878; * Goat Anti-Rabbit IgG (H+L) Antibody; HRP conjugated #MBS7053510; * HA-Tag Monoclonal Antibody #MBS7135631; * E-Tag Monoclonal Antibody #MBS7135632; * TUBA1A Monoclonal Antibody #MBS7135645; * TUBB Monoclonal Antibody #MBS9018332
• Preparation and Storage: Upon receipt, store at -20 degree C or -80 degree C. Avoid repeated freeze.

NCBI and Uniprot Product Information

• NCBI GI #: 6324093
• NCBI GeneID: 855485
• NCBI Accession #: NP_014163.1
• NCBI GenBank Nucleotide #: NM_001183074.1
• UniProt Accession #: P32259; D6W0V7
• Molecular Weight: 111,297 Da
• NCBI Official Full Name: Sin4p
• NCBI Official Symbol: SIN4
• NCBI Official Synonym Symbols: BEL2; GAL22; MED16; RYE1; SDI3; SSF5; SSN4; SSX3; TSF3
• NCBI Protein Information: Sin4p
• UniProt Protein Name: Mediator of RNA polymerase II transcription subunit 16
• Protein Family: Mediator of RNA polymerase II transcription
• UniProt Gene Name: SIN4
• UniProt Synonym Gene Names: BEL2; GAL22; MED16; RYE1; SDI3; SSF5; SSN4; TSF3

Uniprot Description

Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. The Mediator complex, having a compact conformation in its free form, is recruited to promoters by direct interactions with regulatory proteins and serves for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. The Mediator complex unfolds to an extended conformation and partially surrounds RNA polymerase II, specifically interacting with the unphosphorylated form of the C-terminal domain (CTD) of RNA polymerase II. The Mediator complex dissociates from the RNA polymerase II holoenzyme and stays at the promoter when transcriptional elongation begins.