Rabbit anti-Human, Mouse SIDT2 Polyclonal Antibody | anti-SIDT2 antibody

SIDT2, ID (SIDT2, SID1 transmembrane family member 2) (APC)

Cat. Num. AAA6347561

• Gene Names: SIDT2; CGI-40
• Reactivity: Human, Mouse
• Applications: Western Blot
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: SIDT2; Polyclonal Antibody; ID (SIDT2; SID1 transmembrane family member 2) (APC); SID1 transmembrane family member 2; anti-SIDT2 antibody

• Host: Rabbit
• Reactivity: Human, Mouse
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Allophycocyanin (APC).

• Applicable Applications for anti-SIDT2 antibody: Western Blot (WB), FLISA
• Application Notes: WB: 1:100-500; FLISA: 1:1,000; Applications are based on unconjugated antibody.
• Immunogen: SIDT2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 417-447 amino acids from the Central region of human SIDT2.
• Conjugate: APC
• Note: Preservative Free
• Special Handling: Light sensitive
• Preparation and Storage: Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: APC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Western Blot (WB)

(SIDT2 Antibody (Center) western blot analysis in human placenta tissue lysates (35ug/lane).This demonstrates the SIDT2 antibody detected the SIDT2 protein (arrow).)

Western Blot (WB)

(SIDT2 Antibody (Center) western blot analysis in mouse NIH-3T3 cell line lysates (35ug/lane).This demonstrates the SIDT2 antibody detected the SIDT2 protein (arrow).)

Related Product Information for anti-SIDT2 antibody

SIDT2 belongs to the SID1 family. It is a multi-pass membrane protein. The exact function of SIDT2 remains unknown.

Product Categories/Family for anti-SIDT2 antibody

Antibodies; Transmembrane Proteins

References

Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010). Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010): Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009). Olsen, J.V., et al. Cell 127(3):635-648(2006). Olsen, J.V., et al. Cell 127(3):635-648(2006).

NCBI and Uniprot Product Information

• NCBI GI #: 94721340
• NCBI GeneID: 51092
• NCBI Accession #: NP_001035545.1
• NCBI GenBank Nucleotide #: NM_001040455.1
• UniProt Accession #: Q8NBJ9; Q8NBY7; Q9Y357
• Molecular Weight: 95,666 Da
• NCBI Official Full Name: SID1 transmembrane family member 2
• NCBI Official Synonym Full Names: SID1 transmembrane family, member 2
• NCBI Official Symbol: SIDT2
• NCBI Official Synonym Symbols: CGI-40
• NCBI Protein Information: SID1 transmembrane family member 2
• UniProt Protein Name: SID1 transmembrane family member 2
• Protein Family: SID1 transmembrane family
• UniProt Gene Name: SIDT2
• UniProt Entry Name: SIDT2_HUMAN

Uniprot Description

SIDT2: Belongs to the SID1 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, multi-pass; Membrane protein, integral

Chromosomal Location of Human Ortholog: 11q23.3

Cellular Component: lysosomal membrane; integral to membrane

Molecular Function: RNA transmembrane transporter activity

Biological Process: response to glucose stimulus; cell morphogenesis; dsRNA transport; glucose homeostasis