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Western Blot (WB) (Western blot (WB) analysis of SH3GLB2 polyclonal antibody at 1:500 dilutionLaneA: BV2 whole cell lysateLaneB: PC12 whole cell lysate)

Rabbit SH3GLB2 Polyclonal Antibody | anti-SH3GLB2 antibody

SH3GLB2 polyclonal antibody

Gene Names
SH3GLB2; RRIG1; PP6569; PP9455
Reactivity
Human, Mouse, Rat
Applications
Western Blot, Immunohistochemistry
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE)
Synonyms
SH3GLB2; Polyclonal Antibody; SH3GLB2 polyclonal antibody; Endophilin-B2; SH3 domain-containing GRB2-like protein B2; KIAA1848; PP578; anti-SH3GLB2 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
Rabbit IgG
Specificity
SH3GLB2 polyclonal antibody detects endogenous levels of SH3GLB2 protein.
Purity/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE)
Form/Format
PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Concentration
1mg/ml (varies by lot)
Applicable Applications for anti-SH3GLB2 antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
WB: 1:500~1:1000
IHC: 1:50~1:200
Immunogen
Synthetic peptide, corresponding to Human SH3GLB2
Preparation and Storage
Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.

Western Blot (WB)

(Western blot (WB) analysis of SH3GLB2 polyclonal antibody at 1:500 dilutionLaneA: BV2 whole cell lysateLaneB: PC12 whole cell lysate)

Western Blot (WB) (Western blot (WB) analysis of SH3GLB2 polyclonal antibody at 1:500 dilutionLaneA: BV2 whole cell lysateLaneB: PC12 whole cell lysate)
Related Product Information for anti-SH3GLB2 antibody
The Endophilins comprise a family of proteins that associate with Amphiphysin, Synaptojanin and Dynamin and are implicated in presynaptic vesicle trafficking at nerve terminals. The expression patterns of the Endophilins are consistent with their cellular functions at the neuronal synapse. Endophilin B1 is a member of the B subgroup of the Endophilin family that is required for maintenance of mitochondrial morphology and for the regulation of the outer mitochondrial membrane dynamics. Endophilin B2 is also a member of the Endophilin B subroup that is ubiquitously expressed but shows highest levels in brain, adult lung, ovary, and spinal cord. Decreased levels of Endophilin B2 are found in Down Syndrome and may reflect brain dysgenesis.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
43,974 Da
NCBI Official Full Name
endophilin-B2
NCBI Official Synonym Full Names
SH3-domain GRB2-like endophilin B2
NCBI Official Symbol
SH3GLB2
NCBI Official Synonym Symbols
RRIG1; PP6569; PP9455
NCBI Protein Information
endophilin-B2; SH3-containing protein SH3GLB2; retinoid receptor-induced gene 1; SH3 domain-containing GRB2-like protein B2
UniProt Protein Name
Endophilin-B2
Protein Family
UniProt Gene Name
SH3GLB2
UniProt Synonym Gene Names
KIAA1848
UniProt Entry Name
SHLB2_HUMAN

Uniprot Description

SH3GLB2: Belongs to the endophilin family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Autophagy

Chromosomal Location of Human Ortholog: 9q34

Cellular Component: nucleoplasm; cytoplasm; nucleus

Molecular Function: protein binding

Research Articles on SH3GLB2

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Product Notes

The SH3GLB2 sh3glb2 (Catalog #AAA3014911) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The SH3GLB2 polyclonal antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's SH3GLB2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC). WB: 1:500~1:1000 IHC: 1:50~1:200. Researchers should empirically determine the suitability of the SH3GLB2 sh3glb2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SH3GLB2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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