Immunohistochemistry (IHC)
(Anti-SH3GLB1/Bif/Endophilin B1 antibody IHC staining of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 2.5 ug/ml.)
Goat SH3GLB1/Bif/Endophilin B1 Polyclonal Antibody | anti-SH3GLB1 antibody
Anti-SH3GLB1/Bif/Endophilin B1 Antibody (aa373-386)
Predicted: Xenopus, Chicken, Zebrafish, Rat, Hamster, Rabbit, Mouse, Monkey
Predicted: Xenopus, Chicken, Zebrafish, Rat, Hamster, Rabbit, Mouse, Monkey
IHC-P: 2.5 ug/ml
WB: 0.3-1 ug/ml
Avoid freeze-thaw cycles.
Immunohistochemistry (IHC)
(Anti-SH3GLB1/Bif/Endophilin B1 antibody IHC staining of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 2.5 ug/ml.)
Immunohistochemistry (IHC)
(Anti-SH3GLB1/Bif/Endophilin B1 antibody IHC staining of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 2.5 ug/ml.)
Western Blot (WB)
(Staining (0.3?g/ml) of Jurkat lysate (RIPA buffer, 35?g total protein per lane). Primary incubated for 1 hour. Detected by chemiluminescence.)
Western Blot (WB)
(Staining (0.3?g/ml) of Jurkat lysate (RIPA buffer, 35?g total protein per lane). Primary incubated for 1 hour. Detected by chemiluminescence.)
Western Blot (WB)
(Staining (0.3 ug/ml) of Jurkat lysate (RIPA buffer, 35 ug total protein per lane). Primary incubated for 1 hour. Detected by chemiluminescence.)
Western Blot (WB)
(Staining (0.3 ug/ml) of Jurkat lysate (RIPA buffer, 35 ug total protein per lane). Primary incubated for 1 hour. Detected by chemiluminescence.)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a SRC homology 3 domain-containing protein. The encoded protein interacts with the proapoptotic member of the Bcl-2 family, Bcl-2-associated X protein (Bax) and may be involved in regulating apoptotic signaling pathways. This protein may also be involved in maintaining mitochondrial morphology. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2011]
Uniprot Description
May be required for normal outer mitochondrial membrane dynamics (PubMed:15452144). Required for coatomer-mediated retrograde transport in certain cells (). May recruit other proteins to membranes with high curvature. May promote membrane fusion (PubMed:11604418). Involved in activation of caspase-dependent apoptosis by promoting BAX/BAK1 activation (PubMed:16227588). Isoform 1 acts proapoptotic in fibroblasts (). Involved in caspase-independent apoptosis during nutrition starvation and involved in the regulation of autophagy. Activates lipid kinase activity of PIK3C3 during autophagy probably by associating with the PI3K complex II (PI3KC3-C2) (PubMed:17891140). Associated with PI3KC3-C2 during autophagy may regulate the trafficking of ATG9A from the Golgi complex to the peripheral cytoplasm for the formation of autophagosomes by inducing Golgi membrane tubulation and fragmentation (PubMed:21068542). Involved in regulation of degradative endocytic trafficking and cytokinesis, probably in the context of PI3KC3-C2 (PubMed:20643123). Isoform 2 acts antiapoptotic in neuronal cells; involved in maintenance of mitochondrial morphology and promotes neuronal viability ().
Research Articles on SH3GLB1
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Product Notes
The SH3GLB1 sh3glb1 (Catalog #AAA2401019) is an Antibody produced from Goat and is intended for research purposes only. The product is available for immediate purchase. The Anti-SH3GLB1/Bif/Endophilin B1 Antibody (aa373-386) reacts with Human Predicted: Xenopus, Chicken, Zebrafish, Rat, Hamster, Rabbit, Mouse, Monkey and may cross-react with other species as described in the data sheet. AAA Biotech's SH3GLB1/Bif/Endophilin B1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC) Paraffin, Western Blot (WB). ELISA: 1:32000 IHC-P: 2.5 ug/ml WB: 0.3-1 ug/ml. Researchers should empirically determine the suitability of the SH3GLB1 sh3glb1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SH3GLB1/Bif/Endophilin B1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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