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Western Blot (WB) (Western Blot analysis of SH3GL2 in Human cerebrum tissue, Mouse brain tissue, Human cerebella tissue lysates in order using SH3GL2 Rabbit pAb at dilution 1/500)

Rabbit SH3GL2 Polyclonal Antibody | anti-SH3GL2 antibody

SH3GL2 Rabbit pAb

Gene Names
SH3GL2; CNSA2; SH3P4; EEN-B1; SH3D2A
Reactivity
Human, Mouse, Rat
Applications
Western Blot, Immunohistochemistry
Purity
Affinity purified
Synonyms
SH3GL2; Polyclonal Antibody; SH3GL2 Rabbit pAb; SH3 domain containing GRB2 like 2; endophilin A1; CNSA2; SH3P4; EEN-B1; SH3D2A; anti-SH3GL2 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Affinity purified
Form/Format
pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Concentration
1.38mg/ml (varies by lot)
Applicable Applications for anti-SH3GL2 antibody
Western Blot (WB), Immunohistochemistry-Paraffin (IHC-P)
Application Notes
WB: 1:500-1:2000
IHC-P: 1:50-1:200
Immunogen
Fusion protein of human SH3GL2
Conjugation
Unconjugated
Modification
Unmodified
Preparation and Storage
Store at 4 degree C for short term. Store at -20 degree C for long term. Avoid freeze/thaw cycle.

Western Blot (WB)

(Western Blot analysis of SH3GL2 in Human cerebrum tissue, Mouse brain tissue, Human cerebella tissue lysates in order using SH3GL2 Rabbit pAb at dilution 1/500)

Western Blot (WB) (Western Blot analysis of SH3GL2 in Human cerebrum tissue, Mouse brain tissue, Human cerebella tissue lysates in order using SH3GL2 Rabbit pAb at dilution 1/500)

Immunohistochemistry (IHC)

(Immunohistochemistry of SH3GL2 in paraffin-embedded Human liver cancer tissue using SH3GL2 Rabbit pAb at dilution 1/80. Predicted cell location: Cytoplasm)

Immunohistochemistry (IHC) (Immunohistochemistry of SH3GL2 in paraffin-embedded Human liver cancer tissue using SH3GL2 Rabbit pAb at dilution 1/80. Predicted cell location: Cytoplasm)
Related Product Information for anti-SH3GL2 antibody
Implicated in synaptic vesicle endocytosis. May recruit other proteins to membranes with high curvature. Required for BDNF-dependent dendrite outgrowth. Cooperates with SH3GL2 to mediate BDNF-NTRK2 early endocytic trafficking and signaling from early endosomes.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
39,962 Da
NCBI Official Full Name
endophilin-A1
NCBI Official Synonym Full Names
SH3-domain GRB2-like 2
NCBI Official Symbol
SH3GL2
NCBI Official Synonym Symbols
CNSA2; SH3P4; EEN-B1; SH3D2A
NCBI Protein Information
endophilin-A1; endophilin-1; SH3 domain protein 2A; Endophilin A1 BAR domain; bA335L15.1 (SH3-domain GRB2-like 2); SH3 domain-containing GRB2-like protein 2
UniProt Protein Name
Endophilin-A1
Protein Family
UniProt Gene Name
SH3GL2
UniProt Synonym Gene Names
CNSA2; SH3D2A
UniProt Entry Name
SH3G2_HUMAN

Uniprot Description

endophilin 1: Implicated in synaptic vesicle endocytosis. May recruit other proteins to membranes with high curvature. Belongs to the endophilin family.

Protein type: Membrane protein, peripheral; Vesicle; Adaptor/scaffold

Chromosomal Location of Human Ortholog: 9p22

Cellular Component: Golgi membrane; plasma membrane; cytosol

Molecular Function: identical protein binding; protein binding; lipid binding

Biological Process: epidermal growth factor receptor signaling pathway; negative regulation of epidermal growth factor receptor signaling pathway; axon guidance; central nervous system development; nerve growth factor receptor signaling pathway; regulation of receptor internalization; synaptic vesicle endocytosis; antigen processing and presentation of exogenous peptide antigen via MHC class II; post-Golgi vesicle-mediated transport; signal transduction

Research Articles on SH3GL2

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Product Notes

The SH3GL2 sh3gl2 (Catalog #AAA4759164) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The SH3GL2 Rabbit pAb reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's SH3GL2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry-Paraffin (IHC-P). WB: 1:500-1:2000 IHC-P: 1:50-1:200. Researchers should empirically determine the suitability of the SH3GL2 sh3gl2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SH3GL2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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