Testing Data
(Sample (30 ug of whole cell lysate) A: Hep G2 B: Raji 10% SDS PAGE Primary antibody diluted at 1: 1000)
Rabbit anti-Human SH3GL1 Polyclonal Antibody | anti-SH3GL1 antibody
SH3GL1 antibody
Immunohistochemistry: 1:100-1:250
Immunofluorescence: 1:100-1:200
Testing Data
(Sample (30 ug of whole cell lysate) A: Hep G2 B: Raji 10% SDS PAGE Primary antibody diluted at 1: 1000)
Testing Data
(Sample (30 ug of whole cell lysate) A: Hep G2 B: Raji 10% SDS PAGE Primary antibody diluted at 1: 1000)
Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded Breast ca, using EEN antibody at 1: 250 dilution.)
Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded Breast ca, using EEN antibody at 1: 250 dilution.)
Immunofluorescence (IF)
(Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using SH3GL1 antibody at 1: 200 dilution.)
Immunofluorescence (IF)
(Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using SH3GL1 antibody at 1: 200 dilution.)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the endophilin family of Src homology 3 domain-containing proteins. The encoded protein is involved in endocytosis and may also play a role in the cell cycle. Overexpression of this gene may play a role in leukemogenesis, and the encoded protein has been implicated in acute myeloid leukemia as a fusion partner of the myeloid-lymphoid leukemia protein. Pseudogenes of this gene are located on the long arm of chromosomes 11 and 17. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011]
Uniprot Description
SH3GL1: Implicated in endocytosis. May recruit other proteins to membranes with high curvature. In some cases of acute leukemia, a translocation results in the formation of a MLL-EEN fusion gene. Belongs to the endophilin family.
Protein type: Oncoprotein; Vesicle
Chromosomal Location of Human Ortholog: 19p13.3
Cellular Component: cell projection; early endosome membrane; cytoplasm; podosome; cell junction
Molecular Function: identical protein binding; protein binding; GTPase binding; lipid binding; phosphatase binding
Biological Process: central nervous system development; endocytosis; signal transduction
Disease: Leukemia, Acute Myeloid
Research Articles on SH3GL1
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Product Notes
The SH3GL1 sh3gl1 (Catalog #AAA9401584) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The SH3GL1 antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's SH3GL1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF). Western blotting: 1:500-1:3000 Immunohistochemistry: 1:100-1:250 Immunofluorescence: 1:100-1:200. Researchers should empirically determine the suitability of the SH3GL1 sh3gl1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SH3GL1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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