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Western Blot (WB) (Western blotAll lanes: SH3GL1 antibody at 2.48ug/mlLane 1 : HT29 whole cell lysateLane 2 : 293T whole cell lysateSecondaryGoat polyclonal to Rabbit IgG at 1/10000 dilutionPredicted band size: 42,37,35 kDaObserved band size: 41 kDa)

Rabbit anti-Human SH3GL1 Polyclonal Antibody | anti-SH3GL1 antibody

SH3GL1 Antibody

Gene Names
SH3GL1; EEN; CNSA1; SH3P8; SH3D2B
Reactivity
Human
Applications
ELISA, Western Blot, Immunohistochemistry
Purity
Antigen Affinity Purified
Synonyms
SH3GL1; Polyclonal Antibody; SH3GL1 Antibody; Endophilin-A2; EEN fusion partner of MLL; Endophilin-2; Extra eleven-nineteen leukemia fusion gene protein; EEN; SH3 domain protein 2B; SH3 domain-containing GRB2-like protein 1; CNSA1; SH3D2B; anti-SH3GL1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen Affinity Purified
Form/Format
Liquid
Sequence Length
320
Applicable Applications for anti-SH3GL1 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Species
Human
Immunogen
Recombinant human Endophilin-A2 protein (C-150AA)
Conjugate
Non-conjugated
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-10878 / sc-10876 / sc-30101 / sc-25495
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.

Western Blot (WB)

(Western blotAll lanes: SH3GL1 antibody at 2.48ug/mlLane 1 : HT29 whole cell lysateLane 2 : 293T whole cell lysateSecondaryGoat polyclonal to Rabbit IgG at 1/10000 dilutionPredicted band size: 42,37,35 kDaObserved band size: 41 kDa)

Western Blot (WB) (Western blotAll lanes: SH3GL1 antibody at 2.48ug/mlLane 1 : HT29 whole cell lysateLane 2 : 293T whole cell lysateSecondaryGoat polyclonal to Rabbit IgG at 1/10000 dilutionPredicted band size: 42,37,35 kDaObserved band size: 41 kDa)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human placenta tissue using MBS7045973 at dilution 1:100)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human placenta tissue using MBS7045973 at dilution 1:100)
Related Product Information for anti-SH3GL1 antibody
Implicated in endocytosis. May recruit other proteins to membranes with high curvature (By similarity).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
34,519 Da
NCBI Official Full Name
endophilin-A2 isoform 2
NCBI Official Synonym Full Names
SH3 domain containing GRB2 like 1, endophilin A2
NCBI Official Symbol
SH3GL1
NCBI Official Synonym Symbols
EEN; CNSA1; SH3P8; SH3D2B
NCBI Protein Information
endophilin-A2
UniProt Protein Name
Endophilin-A2
Protein Family
UniProt Gene Name
SH3GL1
UniProt Synonym Gene Names
CNSA1; SH3D2B; EEN
UniProt Entry Name
SH3G1_HUMAN

NCBI Description

This gene encodes a member of the endophilin family of Src homology 3 domain-containing proteins. The encoded protein is involved in endocytosis and may also play a role in the cell cycle. Overexpression of this gene may play a role in leukemogenesis, and the encoded protein has been implicated in acute myeloid leukemia as a fusion partner of the myeloid-lymphoid leukemia protein. Pseudogenes of this gene are located on the long arm of chromosomes 11 and 17. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011]

Uniprot Description

SH3GL1: Implicated in endocytosis. May recruit other proteins to membranes with high curvature. In some cases of acute leukemia, a translocation results in the formation of a MLL-EEN fusion gene. Belongs to the endophilin family.

Protein type: Oncoprotein; Vesicle

Chromosomal Location of Human Ortholog: 19p13.3

Cellular Component: cytoplasm

Molecular Function: identical protein binding; protein binding

Biological Process: central nervous system development; signal transduction

Disease: Leukemia, Acute Myeloid

Research Articles on SH3GL1

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Product Notes

The SH3GL1 sh3gl1 (Catalog #AAA7045973) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The SH3GL1 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's SH3GL1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC). Researchers should empirically determine the suitability of the SH3GL1 sh3gl1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SH3GL1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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