Rabbit anti-Human, Mouse SGTA Polyclonal Antibody | anti-SGTA antibody

SGTA (Small Glutamine-rich Tetratricopeptide Repeat-containing Protein alpha, Alpha-SGT, Vpu-binding protein, UBP, SGT, SGT1) (Biotin)

Cat. Num. AAA6394049

• Gene Names: SGTA; SGT; hSGT; alphaSGT
• Reactivity: Human, Mouse
• Applications: Western Blot
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: SGTA; Polyclonal Antibody; SGTA (Small Glutamine-rich Tetratricopeptide Repeat-containing Protein alpha; Alpha-SGT; Vpu-binding protein; UBP; SGT; SGT1) (Biotin); anti-SGTA antibody

• Host: Rabbit
• Reactivity: Human, Mouse
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Recognizes human SGTA. Species Crossreactivity: mouse.
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Biotin.

• Applicable Applications for anti-SGTA antibody: Western Blot (WB)
• Application Notes: Applications are based on unconjugated antibody.
• Immunogen: Full length human SGTA, aa1-313 (NP_003012.1).
• Immunogen Sequence: MDNKKRLAYAIIQFLHDQLRHGGLSSDAQESLEVAIQCLETAFGVTVEDSDLALPQTLPEIFEAAATGKEMPQDLRSPARTPPSEEDSAEAERLKTEGNEQMKVENFEAAVHFYGKAIELNPANAVYFCNRAAAYSKLGNYAGAVQDCERAICIDPAYSKAYGRMGLALSSLNKHVEAVAYYKKALELDPDNETYKSNLKIAELKLREAPSPTGGVGSFDIAGLLNNPGFMSMASNLMNNPQIQQLMSGMISGGNNPLGTPGTSPSQNDLASLIQAGQQFAQQMQQQNPELIEQLRSQIRSRTPSASNDDQQE
• Conjugate: Biotin
• Note: Preservative Free
• Preparation and Storage: Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(SGTA rabbit polyclonal antibody. Western Blot analysis of SGTA expression in human liver.)

Western Blot (WB)

(SGTA rabbit polyclonal antibody. Western Blot analysis of SGTA expression in mouse kidney.)

Western Blot (WB)

(Western Blot analysis of SGTA expression in transfected 293T cell line by SGTA rabbit polyclonal antibody. Lane 1: SGTA transfected lysate (34.1kD). Lane 2: Non-transfected lysate.)

Related Product Information for anti-SGTA antibody

This gene encodes a protein which is capable of interacting with the major nonstructural protein of parvovirus H-1 and 70kD heat shock cognate protein; however, its function is not known. Since this transcript is expressed ubiquitously in various tissues, this protein may serve a housekeeping function. [provided by RefSeq].

Product Categories/Family for anti-SGTA antibody

Antibodies; Tetratricopeptide Repeat Proteins

NCBI and Uniprot Product Information

• NCBI GI #: 4506921
• NCBI GeneID: 6449
• NCBI Accession #: NP_003012.1
• NCBI GenBank Nucleotide #: NM_003021
• UniProt Accession #: O43765; Q6FIA9; Q9BTZ9; D6W610
• Molecular Weight: 34,063 Da
• NCBI Official Full Name: small glutamine-rich tetratricopeptide repeat-containing protein alpha
• NCBI Official Synonym Full Names: small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
• NCBI Official Symbol: SGTA
• NCBI Official Synonym Symbols: SGT; hSGT; alphaSGT
• NCBI Protein Information: small glutamine-rich tetratricopeptide repeat-containing protein alpha; UBP; alpha-SGT; protein containing three tetratricopeptide repeats; vpu-binding protein
• UniProt Protein Name: Small glutamine-rich tetratricopeptide repeat-containing protein alpha
• Protein Family: Small glutamine-rich tetratricopeptide repeat-containing protein
• UniProt Gene Name: SGTA
• UniProt Synonym Gene Names: SGT; SGT1; UBP
• UniProt Entry Name: SGTA_HUMAN

NCBI Description

This gene encodes a protein which is capable of interacting with the major nonstructural protein of parvovirus H-1 and 70-kDa heat shock cognate protein; however, its function is not known. Since this transcript is expressed ubiquitously in various tissues, this protein may serve a housekeeping function. [provided by RefSeq, Jul 2008]

Uniprot Description

SGTA: Co-chaperone that binds directly to HSC70 and HSP70 and regulates their ATPase activity. Homooligomerize. Interacts with NS1 from parvovirus H-1, with Vpu and Gag from HIV-1. Interacts with SARS- CoV accessory protein 7a. Interacts with DNAJC5 and DNAJC5B. Ubiquitous. Belongs to the SGT family.

Protein type: Chaperone

Chromosomal Location of Human Ortholog: 19p13

Cellular Component: cytoplasm

Molecular Function: protein binding

Biological Process: viral reproduction