Rabbit anti-Human SGLT-1 Polyclonal Antibody | anti-slc5a11 antibody
SGLT-1 (Sodium Glucose Transporter 1)
Gene Names
slc5a11; SGLT-1-like; sglt-1-like-a
Reactivity
Human
Applications
ELISA, Western Blot
Purity
SerumSerum
Synonyms
SGLT-1; Polyclonal Antibody; SGLT-1 (Sodium Glucose Transporter 1); Anti -SGLT-1 (Sodium Glucose Transporter 1); anti-slc5a11 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes human SGLT-1. No significant sequence homology exists with other SGLTs. Species sequence homology (56%): mouse, rat. For mouse and rat, we recommend S1010-86D or S1010-86G.
Purity/Purification
Serum
Serum
Serum
Form/Format
Supplied as a liquid in PBS, 0.05% sodium azide.
Applicable Applications for anti-slc5a11 antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes
Suitable for use in ELISA and Western Blot.
Dilution: Western Blot: 1:1000-1:5000 (ECL). Detects a band at ~70-77kD.
ELISA: 1:10,000-1:50,000. Coat ELISA plates at 1ug/ml with control peptide.
Dilution: Western Blot: 1:1000-1:5000 (ECL). Detects a band at ~70-77kD.
ELISA: 1:10,000-1:50,000. Coat ELISA plates at 1ug/ml with control peptide.
Immunogen
Synthetic peptide corresponding to 16aa sequence from the C-terminal, cytoplasmic domain 6 of human SGLT-1 conjugated to KLH.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Related Product Information for anti-slc5a11 antibody
The kidneys play a major role in the regulation of glucose levels. Kidneys filter approx. 180g of glucose per day from the blood, and this is mostly reabsorbed back into the blood in the proximal tubules. Typically, glucose is first absorbed within epithelium by a specific transporter protein, Sodium glucoseco transporters (SGLT), in the brush-border membrane and then it is transported out of the cell across the basolateral membranes by a facilitated sugar transporter (GLUTs). At least 3 members of SGLTs (SGLT1-3) have been cloned and characterized from various species. Individual member of this family have identical predicted secondary structures with up to 14 transmembrane domains. SGLT1-3 genes code for protein of approx 659-672 residues (calculated size of ~75kD). Both N and C-termini are predicted to be extracellualr. There is approx 60-70% homology between SGLT1-3. SGLTs transport a-methyl-D-glucoside (a-MDG), a non-metabolized model substrate, in Na-dependent manner. SGLT1 does not discriminate a-MDG, glucose, and galactose. SGLT2/3 do not transport D-galactose efficiently.
Product Categories/Family for anti-slc5a11 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
NCBI Official Full Name
solute carrier family 5 (sodium/inositol cotransporter), member 11
NCBI Official Synonym Full Names
solute carrier family 5 (sodium/inositol cotransporter), member 11<
NCBI Official Symbol
slc5a11
NCBI Official Synonym Symbols
SGLT-1-like; sglt-1-like-a
NCBI Protein Information
solute carrier family 5 (sodium/inositol cotransporter), member 11; solute carrier family 5 (sodium/inositol cotransporter), member 11; Na+-glucose cotransporter type 1 (SGLT-1)-like protein; solute carrier family 5 (sodium/glucose cotransporter), member 11
Protein Family
Similar Products
Product Notes
The slc5a11 (Catalog #AAA610816) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The SGLT-1 (Sodium Glucose Transporter 1) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's SGLT-1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB). Suitable for use in ELISA and Western Blot. Dilution: Western Blot: 1:1000-1:5000 (ECL). Detects a band at ~70-77kD. ELISA: 1:10,000-1:50,000. Coat ELISA plates at 1ug/ml with control peptide. Researchers should empirically determine the suitability of the slc5a11 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SGLT-1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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