Rabbit SFT2D3 Polyclonal Antibody | anti-SFT2D3 antibody

SFT2D3 Polyclonal Antibody

Cat. Num. AAA3007386

• Reactivity: Human, Mouse, Rat
• Applications: Western Blot
• Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
• Synonyms: SFT2D3; Polyclonal Antibody; SFT2D3 Polyclonal Antibody; Vesicle transport protein SFT2C; SFT2 domain-containing protein 3; anti-SFT2D3 antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: SFT2D3 polyclonal antibody detects endogenous levels of SFT2D3 protein.
• Purity/Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
• Form/Format: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
• Sequence Length: 215

• Applicable Applications for anti-SFT2D3 antibody: Western Blot (WB)
• Application Notes: WB: 1:500-1:1000
• Immunogen: Synthetic peptide, corresponding to amino acids 101-146 of Human SFT2D3.
• Preparation and Storage: Store at 4 degree C short term.; Aliquot and store at -20 degree C long term.; Avoid freeze-thaw cycles.

Western Blot (WB)

(Western Blot (WB) analysis of SFT2D3 polyclonal antibody at 1:500 dilutionLane1:PC12 whole cell lysate (40ug) Lane2:Jurkat whole cell lysat (40ug) Lane3:NIH-3T3 whole cell lysate (40ug))

Related Product Information for anti-SFT2D3 antibody

SFT2D3 (SFT2 domain-containing protein 3) is a 215 amino acid multi-pass membrane protein that belongs to the SFT2 family. SFT2D3 may be involved in fusion of retrograde transport vesicles derived from an endocytic compartment with the Golgi complex. The SFT2D3 gene is conserved in chimpanzee, cow, mouse, rat, zebrafish, fruit fly, mosquito and C.elegans, and maps to human chromosome 2q14.3. As the second largest human chromosome, chromosome 2 makes up approximately 8% of the human genome and contains 237 million bases encoding over 1, 400 genes. A number of genetic diseases are linked to genes on chromosome 2. Harlequin icthyosis, a rare skin deformity, is associated with mutations in the ABCA12 gene. The lipid metabolic disorder sitosterolemia is associated with ABCG5 and ABCG8. An extremely rare recessive genetic disorder, Alström syndrome, is related to mutations in the ALMS1 gene. Chromosome 2 contains a probable vestigial second centromere as well as vestigial telomeres, which gives credence to the hypothesis that human chromosome 2 formed as a result of an ancient fusion of two ancestral chromosomes, which are still present in modern day apes.

NCBI and Uniprot Product Information

• NCBI GI #: 49355757
• NCBI Accession #: NP_116129
• NCBI GenBank Nucleotide #: NP_116129.3
• UniProt Accession #: Q587I9
• Molecular Weight: ~ 21kDa
• NCBI Official Full Name: vesicle transport protein SFT2C
• UniProt Protein Name: Vesicle transport protein SFT2C
• Protein Family: Vesicle transport protein
• UniProt Gene Name: SFT2D3
• UniProt Entry Name: SFT2C_HUMAN

Uniprot Description

SFT2D3: May be involved in fusion of retrograde transport vesicles derived from an endocytic compartment with the Golgi complex. Belongs to the SFT2 family.

Protein type: Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 2q14.3

Cellular Component: integral to membrane

Biological Process: vesicle-mediated transport; protein transport