anti-Human SEZ6L2 Polyclonal Antibody | anti-SEZ6L2 antibody
SEZ6L2 Antibody, HRP Conjugated
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a seizure-related protein that is localized on the cell surface. The gene is located in a region of chromosome 16p11.2 that is thought to contain candidate genes for autism spectrum disorders (ASD), though there is no evidence directly implicating this gene in ASD. Increased expression of this gene has been found in lung cancers, and the protein is therefore considered to be a novel prognostic marker for lung cancer. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Aug 2011]
Uniprot Description
SEZ6L2: May contribute to specialized endoplasmic reticulum functions in neurons. Belongs to the SEZ6 family. 4 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, integral
Chromosomal Location of Human Ortholog: 16p11.2
Cellular Component: endoplasmic reticulum membrane; plasma membrane; integral to membrane