Immunohistochemistry (IHC)
(Immunochemical staining of human SERINC3 in human kidney with rabbit polyclonal antibody at 1:100 dilution, formalin-fixed paraffin embedded sections.)
Rabbit anti-Human SERINC3 Polyclonal Antibody | anti-SERINC3 antibody
Anti-SERINC3 Antibody, Rabbit Polyclonal
Reactivity
Human
Applications
Immunohistochemistry
Purity
Protein A & Antigen Affinity
Synonyms
SERINC3; Polyclonal Antibody; Anti-SERINC3 Antibody; Rabbit Polyclonal; SERINC3 Antibody; Rabbit PAb; Antigen Affinity Purified; serine incorporator 3; Anti-AIGP1 Antibody; Anti-DIFF33 Antibody; Anti-SBBI99 Antibody; Anti-TDE Antibody; Anti-TDE1 Antibody; Anti-TMS-1 Antibody; anti-SERINC3 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit IgG
Specificity
Human SERINC3
Purity/Purification
Protein A & Antigen Affinity
Form/Format
Liquid; PBS, pH7.0 with 0.03% Proclin300
Applicable Applications for anti-SERINC3 antibody
Immunohistochemistry-Paraffin (IHC-P)
Application Notes
IHC-P: 1:50-1:200
Immunogen
E Coli-derived Human SERINC3 fragment
Conjugation
Unconjugated
Preparation
Produced in rabbits immunized with E Coli-derived Human SERINC3 fragment, and purified by antigen affinity chromatography.
Preparation and Storage
This antibody can be stored at 2-8 degree C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20 degree C to -80 degree C. Avoid repeated freeze-thaw cycles.
Immunohistochemistry (IHC)
(Immunochemical staining of human SERINC3 in human kidney with rabbit polyclonal antibody at 1:100 dilution, formalin-fixed paraffin embedded sections.)
Immunohistochemistry (IHC)
(Immunochemical staining of human SERINC3 in human kidney with rabbit polyclonal antibody at 1:100 dilution, formalin-fixed paraffin embedded sections.)
Related Product Information for anti-SERINC3 antibody
SERINC3 (Serine Incorporator 3) is a Protein Coding gene. The SERINC3 gene, located on 20q13.12, is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, zebrafish, A.thaliana, rice, and frog. Human SERINC5 and SERINC3 were shown to possess antiretroviral activity for some retroviruses, including human immunodeficiency virus (HIV), murine leukemia virus (MLV), and equine infectious anemia virus (EIAV). SERINC3 and SERINC5 were identified as the targets of HIV-1 Nef, a protein crucial for the optimal infectivity of virus particles. SERINC3 is widely expressed in the brain, testis, and other tissues. Diseases associated with SERINC3 include Gerstmann Syndrome and 46, Xy Sex Reversal 8. Among its related pathways are Viral mRNA Translation and Metabolism.
References
Timilsina U, et al. (2020) Serinc5 potently restricts retrovirus infection in vivo. mBio 11 (4): e00588-20.Murrell B, et al. (2016) The evolutionary histories of antiretroviral proteins serinc3 and serinc5 do not support an evolutionary arms race in primates. J Virol 90 (18): 8085-8089.
Similar Products
Product Notes
The SERINC3 (Catalog #AAA8108883) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-SERINC3 Antibody, Rabbit Polyclonal reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's SERINC3 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry-Paraffin (IHC-P). IHC-P: 1:50-1:200. Researchers should empirically determine the suitability of the SERINC3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SERINC3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
