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Western Blot (WB) (Western Blot analysis of extracts of various cell lines, using SEPT8 antibody.)

Rabbit SEPT8 Polyclonal Antibody | anti-SEPT8 antibody

SEPT8 Polyclonal Antibody

Gene Names
SEPTIN8; SEP2; SEPT8
Reactivity
Human, Mouse, Rat
Applications
Western Blot
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
Synonyms
SEPT8; Polyclonal Antibody; SEPT8 Polyclonal Antibody; 43345; anti-SEPT8 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
SEPT8 polyclonal antibody detects endogenous levels of 43351 protein.
Purity/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
Form/Format
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Sequence Length
483
Applicable Applications for anti-SEPT8 antibody
Western Blot (WB)
Application Notes
WB: 1:500-1:2000
Immunogen
Recombinant protein of human SEPT8
Preparation and Storage
Store at 4 degree C short term.
Aliquot and store at -20 degree C long term.
Avoid freeze-thaw cycles.

Western Blot (WB)

(Western Blot analysis of extracts of various cell lines, using SEPT8 antibody.)

Western Blot (WB) (Western Blot analysis of extracts of various cell lines, using SEPT8 antibody.)
Related Product Information for anti-SEPT8 antibody
This gene is a member of the septin family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse, and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
~ 55kDa
NCBI Official Full Name
Septin-8
NCBI Official Synonym Full Names
septin 8
NCBI Official Symbol
SEPTIN8
NCBI Official Synonym Symbols
SEP2; SEPT8
NCBI Protein Information
septin-8
UniProt Protein Name
Septin-8
UniProt Gene Name
SEPT8
UniProt Synonym Gene Names
KIAA0202
UniProt Entry Name
SEPT8_HUMAN

NCBI Description

This gene is a member of the septin family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse, and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014]

Uniprot Description

SEPT8: Filament-forming cytoskeletal GTPase. May play a role in cytokinesis (Potential). May play a role in platelet secretion. Belongs to the septin family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Cytoskeletal; Hydrolase

Chromosomal Location of Human Ortholog: 5q31

Cellular Component: cytoskeleton; cytoplasm

Molecular Function: protein binding; GTP binding

Biological Process: cell cycle

Research Articles on SEPT8

Similar Products

Product Notes

The SEPT8 sept8 (Catalog #AAA3010486) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The SEPT8 Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's SEPT8 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:500-1:2000. Researchers should empirically determine the suitability of the SEPT8 sept8 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SEPT8, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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