Western Blot (WB)
(Western blot analysis of extracts from HuvEc cells, using SENP7 antibody.)
Rabbit anti-Human, Mouse SENP7 Polyclonal Antibody | anti-SENP7 antibody
SENP7 Antibody
IHC: 1:50-1:100
Western Blot (WB)
(Western blot analysis of extracts from HuvEc cells, using SENP7 antibody.)
Western Blot (WB)
(Western blot analysis of extracts from HuvEc cells, using SENP7 antibody.)
Immunohistochemistry (IHC)
(Immunohistochemistry analysis of paraffin-embedded human brain tissue using SENP7 antibody.)
Immunohistochemistry (IHC)
(Immunohistochemistry analysis of paraffin-embedded human brain tissue using SENP7 antibody.)
NCBI and Uniprot Product Information
NCBI Description
The reversible posttranslational modification of proteins by the addition of small ubiquitin-like SUMO proteins (see SUMO1; MIM 601912) is required for many cellular processes. SUMO-specific proteases, such as SENP7, process SUMO precursors to generate a C-terminal diglycine motif required for the conjugation reaction. They also display isopeptidase activity for deconjugation of SUMO-conjugated substrates (Lima and Reverter, 2008 [PubMed 18799455]).[supplied by OMIM, Jun 2009]
Uniprot Description
SENP7: Protease that deconjugates SUMO2 and SUMO3 from targeted proteins, but not SUMO1. Catalyzes the deconjugation of poly-SUMO2 and poly-SUMO3 chains. Has very low efficiency in processing full- length SUMO proteins to their mature forms. Belongs to the peptidase C48 family. 5 isoforms of the human protein are produced by alternative splicing.
Protein type: EC 3.4.22.68; Protease
Chromosomal Location of Human Ortholog: 3q12
Cellular Component: intracellular; nucleus
Molecular Function: protein binding; cysteine-type peptidase activity
Biological Process: proteolysis
Research Articles on SENP7
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Product Notes
The SENP7 senp7 (Catalog #AAA7132165) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The SENP7 Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's SENP7 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC). WB: 1:500-1:3000 IHC: 1:50-1:100. Researchers should empirically determine the suitability of the SENP7 senp7 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SENP7, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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