Rabbit anti-Human Semaphorin 6A Polyclonal Antibody | anti-SEMA6A antibody

Semaphorin 6A (Semaphorin-6A, SEMA6A, HT018, KIAA1368, Semaphorin VIA, Sema VIA, Semaphorin-6A-1, SEMA6A1, SEMA6A-1, SEMAQ, VIA) APC

Cat. Num. AAA6393586

• Gene Names: SEMA6A; VIA; SEMA; HT018; SEMAQ; SEMA6A1
• Reactivity: Human
• Applications: Western Blot
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: Semaphorin 6A; Polyclonal Antibody; Semaphorin 6A (Semaphorin-6A; SEMA6A; HT018; KIAA1368; Semaphorin VIA; Sema VIA; Semaphorin-6A-1; SEMA6A1; SEMA6A-1; SEMAQ; VIA) APC; anti-SEMA6A antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Recognizes human SEMA6A.
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Allophycocyanin (APC).

• Applicable Applications for anti-SEMA6A antibody: Western Blot (WB)
• Application Notes: Applications are based on unconjugated antibody.
• Immunogen: Full length human SEMA6A, aa1-1030 (NP_065847.1).
• Immunogen Sequence: MRSEALLLYFTLLHFAGAGFPEDSEPISISHGNYTKQYPVFVGHKPGRNTTQRHRLDIQMIMIMNGTLYIAARDHIYTVDIDTSHTEEIYCSKKLTWKSRQADVDTCRMKGKHKDECHNFIKVLLKKNDDALFVCGTNAFNPSCRNYKMDTLEPFGDEFSGMARCPYDAKHANVALFADGKLYSATVTDFLAIDAVIYRSLGESPTLRTVKHDSKWLKEPYFVQAVDYGDYIYFFFREIAVEYNTMGKVVFPRVAQVCKNDMGGSQRVLEKQWTSFLKARLNCSVPGDSHFYFNILQAVTDVIRINGRDVVLATFSTPYNSIPGSAVCAYDMLDIASVFTGRFKEQKSPDSTWTPVPDERVPKPRPGCCAGSSSLERYATSNEFPDDTLNFIKTHPLMDEAVPSIFNRPWFLRTMVRYRLTKIAVDTAAGPYQNHTVVFLGSEKGIILKFLARIGNSGFLNDSLFLEEMSVYNSEKCSYDGVEDKRIMGMQLDRASSSLYVAFSTCVIKVPLGRCERHGKCKKTCIASRDPYCGWIKEGGACSHLSPNSRLTFEQDIERGNTDGLGDCHNSFVALNGHSSSLLPSTTTSDSTAQEGYESRGGMLDWKHLLDSPDSTDPLGAVSSHNHQDKKGVIRESYLKGHDQLVPVTLLAIAVILAFVMGAVFSGITVYCVCDHRRKDVAVVQRKEKELTHSRRGSMSSVTKLSGLFGDTQSKDPKPEAILTPLMHNGKLATPGNTAKMLIKADQHHLDLTALPTPESTPTLQQKRKPSRGSREWERNQNLINACTKDMPPMGSPVIPTDLPLRASPSHIPSVVVLPITQQGYQHEYVDQPKMSEVAQMALEDQAATLEYKTIKEHLSSKSPNHGVNLVENLDSLPPKVPQREASLGPPGASLSQTGLSKRLEMHHSSSYGVDYKRSYPTNSLTRSHQATTLKRNNTNSSNSSHLSRNQSFGRGDNPPPAPQRVDSIQVHSSQPSGQAVTVSRQPSLNAYNSLTRSGLKRTPSLKPDVPPKPSFAPLSTSMKPNDACT
• Conjugate: APC
• Note: Preservative Free
• Preparation and Storage: Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: APC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Western Blot (WB)

(Western Blot analysis of SEMA6A expression in transfected 293T cell line by SEMA6A polyclonal antibody. Lane 1: SEMA6A transfected lysate (114.4kD). Lane 2: Non-transfected lysate.)

Product Categories/Family for anti-SEMA6A antibody

Antibodies; Neuroscience

NCBI and Uniprot Product Information

• NCBI GI #: 11991660
• NCBI GeneID: 57556
• NCBI Accession #: NP_065847.1
• NCBI GenBank Nucleotide #: NM_020796
• UniProt Accession #: Q9H2E6; Q9P2H9
• Molecular Weight: 116,336 Da
• NCBI Official Full Name: semaphorin-6A isoform 2
• NCBI Official Synonym Full Names: semaphorin 6A
• NCBI Official Symbol: SEMA6A
• NCBI Official Synonym Symbols: VIA; SEMA; HT018; SEMAQ; SEMA6A1
• NCBI Protein Information: semaphorin-6A
• UniProt Protein Name: Semaphorin-6A
• Protein Family: Semaphorin
• UniProt Gene Name: SEMA6A
• UniProt Synonym Gene Names: KIAA1368; SEMAQ; Sema VIA; SEMA6A-1

NCBI Description

The transmembrane semaphorin SEMA6A is expressed in developing neural tissue and is required for proper development of the thalamocortical projection (Leighton et al., 2001 [PubMed 11242070]).[supplied by OMIM, Feb 2011]

Uniprot Description

Cell surface receptor for PLXNA2 that plays an important role in cell-cell signaling. Required for normal granule cell migration in the developing cerebellum. Promotes reorganization of the actin cytoskeleton and plays an important role in axon guidance in the developing central nervous system. Can act as repulsive axon guidance cue. Has repulsive action towards migrating granular neurons. May play a role in channeling sympathetic axons into the sympathetic chains and controlling the temporal sequence of sympathetic target innervation ().