Western Blot (WB)
(SEMA4C Antibody (C-term) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the SEMA4C antibody detected the SEMA4C protein (arrow).)
Rabbit SEMA4C Polyclonal Antibody | anti-SEMA4C antibody
SEMA4C Antibody (C-term)
Western Blot (WB)
(SEMA4C Antibody (C-term) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the SEMA4C antibody detected the SEMA4C protein (arrow).)
Western Blot (WB)
(SEMA4C Antibody (C-term) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the SEMA4C antibody detected the SEMA4C protein (arrow).)
Flow Cytometry (FC/FACS)
(SEMA4C Antibody (C-term) flow cytometric analysis of K562 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated donkey-anti-rabbit secondary antibodies were used for the analysis.)
Flow Cytometry (FC/FACS)
(SEMA4C Antibody (C-term) flow cytometric analysis of K562 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated donkey-anti-rabbit secondary antibodies were used for the analysis.)
Clark, H.F., et al. Genome Res. 13(10):2265-2270(2003)
Inagaki, S., et al. J. Biol. Chem. 276(12):9174-9181(2001)
Ohoka, Y., et al. Biochem. Biophys. Res. Commun. 280(1):237-243(2001)
Wang, L.H., et al. J. Biol. Chem. 274(20):14137-14146(1999)
NCBI and Uniprot Product Information
Uniprot Description
SEMA4C: Cell surface receptor for PLXNB2 that plays an important role in cell-cell signaling. PLXNB2 binding promotes downstream activation of RHOA and phosphorylation of ERBB2 at 'Tyr-1248'. Required for normal brain development, axon guidance and cell migration. Probable signaling receptor which may play a role in myogenic differentiation through activation of the stress-activated MAPK cascade. Belongs to the semaphorin family.
Protein type: Membrane protein, integral
Chromosomal Location of Human Ortholog: 2q11.2
Cellular Component: postsynaptic membrane; extracellular space; synaptic vesicle membrane; postsynaptic density; integral to membrane; cell junction
Molecular Function: receptor activity
Biological Process: cell migration in hindbrain; muscle cell differentiation; neural tube closure; cerebellum development; positive regulation of stress-activated MAPK cascade
Research Articles on SEMA4C
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Product Notes
The SEMA4C sema4c (Catalog #AAA9203235) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 792-821. The SEMA4C Antibody (C-term) reacts with Human (Predicted Reactivity: Mouse) and may cross-react with other species as described in the data sheet. AAA Biotech's SEMA4C can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA), Flow Cytometry (FC/FACS). WB~~1:1000. Researchers should empirically determine the suitability of the SEMA4C sema4c for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SEMA4C, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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