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Immunohistochemistry (IHC) (Immunohistochemistry analysis of SEMA3C antibody in paraffin-embedded human pancreas tissue.)

Rabbit SEMA3C Polyclonal Antibody | anti-SEMA3C antibody

SEMA3C Antibody

Gene Names
SEMA3C; SemE; SEMAE
Reactivity
Human, Mouse, Rat
Applications
Immunohistochemistry, ELISA
Purity
Purified from rabbit antiserum by affinity-chromatography using immunogen.
Synonyms
SEMA3C; Polyclonal Antibody; SEMA3C Antibody; anti-SEMA3C antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Specificity
SEMA3C antibody detects endogenous levels of SEMA3C.
Purity/Purification
Purified from rabbit antiserum by affinity-chromatography using immunogen.
Form/Format
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1 mg/ml (varies by lot)
Sequence Length
233
Applicable Applications for anti-SEMA3C antibody
Immunohistochemistry (IHC), ELISA (EIA)
Application Notes
IHC: 1:50~1:100
ELISA: 1:10000
Target Modification
Unmodified/Total
Immunogen
The antiserum was produced against synthesized peptide derived from human SEMA3C.
Immunogen Range
701-750
Preparation and Storage
Stable at -20 degree C for at least 1 year.

Immunohistochemistry (IHC)

(Immunohistochemistry analysis of SEMA3C antibody in paraffin-embedded human pancreas tissue.)

Immunohistochemistry (IHC) (Immunohistochemistry analysis of SEMA3C antibody in paraffin-embedded human pancreas tissue.)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
85 kDa
NCBI Official Full Name
semaphorin-3C isoform 2
NCBI Official Synonym Full Names
semaphorin 3C
NCBI Official Symbol
SEMA3C
NCBI Official Synonym Symbols
SemE; SEMAE
NCBI Protein Information
semaphorin-3C
UniProt Protein Name
Semaphorin-3C
Protein Family
UniProt Gene Name
SEMA3C
UniProt Synonym Gene Names
SEMAE; Sema E

NCBI Description

This gene encodes a secreted glycoprotein that belongs to the semaphorin class 3 family of neuronal guidance cues. The encoded protein contains an N-terminal sema domain, integrin and immunoglobulin-like domains, and a C-terminal basic domain. Homodimerization and proteolytic cleavage of the C-terminal propeptide are necessary for the function of the encoded protein. It binds a neuropilin co-receptor before forming a heterotrimeric complex with an associated plexin. An increase in the expression of this gene correlates with an increase in cancer cell invasion and adhesion. Naturally occurring mutations in this gene are associated with Hirschsprung disease. [provided by RefSeq, May 2017]

Uniprot Description

Binds to plexin family members and plays an important role in the regulation of developmental processes. Required for normal cardiovascular development during embryogenesis. Functions as attractant for growing axons, and thereby plays an important role in axon growth and axon guidance ().

Research Articles on SEMA3C

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Product Notes

The SEMA3C sema3c (Catalog #AAA9509043) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The SEMA3C Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's SEMA3C can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC), ELISA (EIA). IHC: 1:50~1:100 ELISA: 1:10000. Researchers should empirically determine the suitability of the SEMA3C sema3c for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SEMA3C, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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