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Western Blot (WB) (Western blot analysis of hromogranin-C Antibody (Center) in Ramos cell line lysates (35ug/lane). SCG2 (arrow) was detected using the purified Pab.)

Rabbit anti-Human Secretogranin II Polyclonal Antibody | anti-SCG2 antibody

Secretogranin II, ID (Secretogranin-2, Chromogranin-C, SgII, Secretoneurin, SN, CHGC, SCG2) (AP)

Gene Names
SCG2; SN; CHGC; EM66; SgII
Reactivity
Human
Applications
Western Blot, ELISA
Purity
Purified by Ammonium Sulfate Precipitation.
Synonyms
Secretogranin II; Polyclonal Antibody; ID (Secretogranin-2; Chromogranin-C; SgII; Secretoneurin; SN; CHGC; SCG2) (AP); anti-SCG2 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes human Chromogranin-C.
Purity/Purification
Purified by Ammonium Sulfate Precipitation.
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phosphatase.
Applicable Applications for anti-SCG2 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB: 1:50-1:100
ELISA: 1:1,000
Applications are based on unconjugated antibody.
Immunogen
Synthetic peptide selected from the center region of human Chromogranin-C (KLH).
Conjugate
AP
Note
Preservative Free
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(Western blot analysis of hromogranin-C Antibody (Center) in Ramos cell line lysates (35ug/lane). SCG2 (arrow) was detected using the purified Pab.)

Western Blot (WB) (Western blot analysis of hromogranin-C Antibody (Center) in Ramos cell line lysates (35ug/lane). SCG2 (arrow) was detected using the purified Pab.)

Immunohistochemistry (IHC)

(Chromogranin-C Antibody (Center) IHC analysis in formalin fixed and paraffin embedded mouse brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the Chromogranin-C Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)

Immunohistochemistry (IHC) (Chromogranin-C Antibody (Center) IHC analysis in formalin fixed and paraffin embedded mouse brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the Chromogranin-C Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)
Product Categories/Family for anti-SCG2 antibody
References
1. Li, L., et.al., Cell Death Differ. 15(5), 879-888 (2008).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
70,941 Da
NCBI Official Full Name
secretogranin-2
NCBI Official Synonym Full Names
secretogranin II
NCBI Official Symbol
SCG2
NCBI Official Synonym Symbols
SN; CHGC; EM66; SgII
NCBI Protein Information
secretogranin-2; chromogranin-C; secretoneurin
UniProt Protein Name
Secretogranin-2
Protein Family
UniProt Gene Name
SCG2
UniProt Synonym Gene Names
CHGC; SgII; SN
UniProt Entry Name
SCG2_HUMAN

Uniprot Description

SCG2: Secretogranin-2 is a neuroendocrine secretory granule protein, which is the precursor for biologically active peptides. Belongs to the chromogranin/secretogranin protein family.

Protein type: Apoptosis; Secreted, signal peptide; Cell cycle regulation; Cytokine; Motility/polarity/chemotaxis; Secreted

Chromosomal Location of Human Ortholog: 2q35-q36

Cellular Component: extracellular space; secretory granule

Molecular Function: cytokine activity; chemoattractant activity

Biological Process: positive chemotaxis; negative regulation of endothelial cell proliferation; MAPKKK cascade; protein secretion; eosinophil chemotaxis; endothelial cell migration; positive regulation of endothelial cell proliferation; angiogenesis; inflammatory response; induction of positive chemotaxis

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Product Notes

The SCG2 scg2 (Catalog #AAA6498659) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Secretogranin II, ID (Secretogranin-2, Chromogranin-C, SgII, Secretoneurin, SN, CHGC, SCG2) (AP) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Secretogranin II can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB: 1:50-1:100 ELISA: 1:1,000 Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the SCG2 scg2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Secretogranin II, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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