Western Blot (WB)
(Western blot analysis of anti-SCYL2 Pab (MBS9208590) in T47D (left) and mouse brain (right) tissue lysates (35ug/lane). SCYL2(arrow) was detected using the purified Pab.)
Rabbit anti-Human, mouse SCYL2 Polyclonal Antibody | anti-SCYL2 antibody
SCYL2 Antibody (C-term)
Western Blot (WB)
(Western blot analysis of anti-SCYL2 Pab (MBS9208590) in T47D (left) and mouse brain (right) tissue lysates (35ug/lane). SCYL2(arrow) was detected using the purified Pab.)
Western Blot (WB)
(Western blot analysis of anti-SCYL2 Pab (MBS9208590) in T47D (left) and mouse brain (right) tissue lysates (35ug/lane). SCYL2(arrow) was detected using the purified Pab.)
Immunohistochemistry (IHC)
(Formalin-fixed and paraffin-embedded human brain tissue reacted with SCYL2 (C-term) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.)
Immunohistochemistry (IHC)
(Formalin-fixed and paraffin-embedded human brain tissue reacted with SCYL2 (C-term) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.)
NCBI and Uniprot Product Information
Uniprot Description
SCYL2: Component of AP2-containing clathrin coated structures at the plasma membrane or of endocytic coated vesicles. According to PubMed:15809293, probable serine/threonine-protein kinase that phosphorylates, in vitro, the beta2-subunit of the plasma membrane adapter complex AP2 and other proteins in presence of poly-L- lysine. According to PubMed:16914521, has no detectable kinase activity in vitro. May regulate clathrin-dependent trafficking between the TGN and/or the endosomal system. Belongs to the protein kinase superfamily.
Protein type: Protein kinase, Ser/Thr (non-receptor); Protein kinase, Other; Kinase, protein; Other group; SCY1 family
Chromosomal Location of Human Ortholog: 12q23.1
Cellular Component: Golgi apparatus; clathrin-coated vesicle; perinuclear region of cytoplasm; endosome membrane
Molecular Function: protein binding; ATP binding; receptor binding; protein kinase activity
Biological Process: positive regulation of receptor internalization; endosome to lysosome transport; protein amino acid phosphorylation
Research Articles on SCYL2
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Product Notes
The SCYL2 scyl2 (Catalog #AAA9208590) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 643-672. The SCYL2 Antibody (C-term) reacts with Human, mouse and may cross-react with other species as described in the data sheet. AAA Biotech's SCYL2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC). WB~~1:1000. Researchers should empirically determine the suitability of the SCYL2 scyl2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SCYL2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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