Western Blot (WB)
(Western Blot analysis of SCNN1D expression in transfected 293T cell line by SCNN1D polyclonal antibody. Lane 1: SCNN1D transfected lysate (70.2kD). Lane 2: Non-transfected lysate.)
Rabbit anti-Human SCNN1D Polyclonal Antibody | anti-SCNN1D antibody
SCNN1D (DNACH, Amiloride-sensitive Sodium Channel Subunit delta, Delta-NaCH, Epithelial Na(+) Channel Subunit delta, Nonvoltage-gated Sodium Channel 1 Subunit delta, SCNED, MGC149710, MGC149711) (HRP)
Gene Names
SCNN1D; ENaCd; SCNED; dNaCh; ENaCdelta
Reactivity
Human
Applications
Western Blot
Purity
Purified by Protein A Affinity Chromatography.
Synonyms
SCNN1D; Polyclonal Antibody; SCNN1D (DNACH; Amiloride-sensitive Sodium Channel Subunit delta; Delta-NaCH; Epithelial Na(+) Channel Subunit delta; Nonvoltage-gated Sodium Channel 1 Subunit delta; SCNED; MGC149710; MGC149711) (HRP); anti-SCNN1D antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes human SCNN1D.
Purity/Purification
Purified by Protein A Affinity Chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Horseradish Peroxidase (HRP).
Applicable Applications for anti-SCNN1D antibody
Western Blot (WB)
Application Notes
Applications are based on unconjugated antibody.
Immunogen
Full length human SCNN1D, aa1-638 (NP_002969.2).
Immunogen Sequence
MAEHRSMDGRMEAATRGGSHLQAAAQTPPRPGPPSAPPPPPKEGHQEGLVELPASFRELLTFFCTNATIHGAIRLVCSRGNRLKTTSWGLLSLGALVALCWQLGLLFERHWHRPVLMAVSVHSERKLLPLVTLCDGNPRRPSPVLRHLELLDEFARENIDSLYNVNLSKGRAALSATVPRHEPPFHLDREIRLQRLSHSGSRVRVGFRLCNSTGGDCFYRGYTSGVAAVQDWYHFHYVDILALLPAAWEDSHGSQDGHFVLSCSYDGLDCQARQFRTFHHPTYGSCYTVDGVWTAQRPGITHGVGLVLRVEQQPHLPLLSTLAGIRVMVHGRNHTPFLGHHSFSVRPGTEATISIREDEVHRLGSPYGHCTAGGEGVEVELLHNTSYTRQACLVSCFQQLMVETCSCGYYLHPLPAGAEYCSSARHPAWGHCFYRLYQDLETHRLPCTSRCPRPCRESAFKLSTGTSRWPSAKSAGWTLATLGEQGLPHQSHRQRSSLAKINIVYQELNYRSVEEAPVYSVPQLLSAMGSLCSLWFGASVLSLLELLELLLDASALTLVLGGRRLRRAWFSWPRASPASGASSIKPEASQMPPPAGGTSDDPEPSGPHLPRVMLPGVLAGVSAEESWAGPQPLETLDT
Conjugate
HRP
Note
Preservative Free
Preparation and Storage
Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Note: Sodium azide is a potent inhibitor of peroxidase and should not be added to HRP conjugates. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Western Blot (WB)
(Western Blot analysis of SCNN1D expression in transfected 293T cell line by SCNN1D polyclonal antibody. Lane 1: SCNN1D transfected lysate (70.2kD). Lane 2: Non-transfected lysate.)
Western Blot (WB)
(Western Blot analysis of SCNN1D expression in transfected 293T cell line by SCNN1D polyclonal antibody. Lane 1: SCNN1D transfected lysate (70.2kD). Lane 2: Non-transfected lysate.)
Related Product Information for anti-SCNN1D antibody
Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Controls the reabsorption of sodium in kidney, colon, lung and sweat glands. Also plays a role in taste perception.
Product Categories/Family for anti-SCNN1D antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
77,442 Da
NCBI Official Synonym Full Names
sodium channel epithelial 1 subunit delta
NCBI Official Symbol
SCNN1D
NCBI Official Synonym Symbols
ENaCd; SCNED; dNaCh; ENaCdelta
NCBI Protein Information
amiloride-sensitive sodium channel subunit delta
UniProt Protein Name
Amiloride-sensitive sodium channel subunit delta
Protein Family
UniProt Gene Name
SCNN1D
UniProt Synonym Gene Names
DNACH; Delta-ENaC; ENaCD
UniProt Entry Name
SCNND_HUMAN
Uniprot Description
ENaC-delta: Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Controls the reabsorption of sodium in kidney, colon, lung and sweat glands. Also plays a role in taste perception. Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. SCNN1D subfamily. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, multi-pass; Channel, sodium; Transporter, ion channel; Membrane protein, integral
Chromosomal Location of Human Ortholog: 1p36.3-p36.2
Cellular Component: membrane; integral to membrane; plasma membrane; actin cytoskeleton
Molecular Function: amiloride-sensitive sodium channel activity; protein binding
Biological Process: sensory perception of taste; sodium ion transport; response to stimulus; transmembrane transport
Research Articles on SCNN1D
Similar Products
Product Notes
The SCNN1D scnn1d (Catalog #AAA6393402) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The SCNN1D (DNACH, Amiloride-sensitive Sodium Channel Subunit delta, Delta-NaCH, Epithelial Na(+) Channel Subunit delta, Nonvoltage-gated Sodium Channel 1 Subunit delta, SCNED, MGC149710, MGC149711) (HRP) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's SCNN1D can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the SCNN1D scnn1d for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SCNN1D, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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