Rabbit anti-Human SCD Polyclonal Antibody | anti-SCD antibody

SCD Rabbit Polyclonal

Cat. Num. AAA7603860

• Gene Names: SCD; SCD1; FADS5; SCDOS; hSCD1; MSTP008
• Reactivity: Human
• Applications: ELISA, Immunohistochemistry
• Purity: >=95% as determined by SDS-PAGE; Immunogen Affinity Purified
• Synonyms: SCD; Polyclonal Antibody; SCD Rabbit Polyclonal; anti-SCD antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: >=95% as determined by SDS-PAGE; Immunogen Affinity Purified
• Form/Format: Liquid
• Sequence Length: 355

• Applicable Applications for anti-SCD antibody: ELISA (EIA), Immunohistochemistry (IHC)
• Immunogen: Stearoyl-CoA desaturase (delta-9-desaturase)
• Preparation and Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20 degree C for 24 months (Avoid repeated freeze / thaw cycles.)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human liver using MBS7603860 (SCD antibody) at dilution of 1:200)

NCBI and Uniprot Product Information

• NCBI GI #: 13543284
• NCBI GeneID: 6319
• Molecular Weight: 41,523 Da
• NCBI Official Full Name: SCD protein
• NCBI Official Synonym Full Names: stearoyl-CoA desaturase
• NCBI Official Symbol: SCD
• NCBI Official Synonym Symbols: SCD1; FADS5; SCDOS; hSCD1; MSTP008
• NCBI Protein Information: acyl-CoA desaturase
• UniProt Protein Name: Acyl-CoA desaturase
• Protein Family: Acyl-CoA desaturase
• UniProt Gene Name: SCD
• UniProt Synonym Gene Names: hSCD1
• UniProt Entry Name: ACOD_HUMAN

NCBI Description

This gene encodes an enzyme involved in fatty acid biosynthesis, primarily the synthesis of oleic acid. The protein belongs to the fatty acid desaturase family and is an integral membrane protein located in the endoplasmic reticulum. Transcripts of approximately 3.9 and 5.2 kb, differing only by alternative polyadenlyation signals, have been detected. A gene encoding a similar enzyme is located on chromosome 4 and a pseudogene of this gene is located on chromosome 17. [provided by RefSeq, Sep 2015]

Uniprot Description

SCD: Terminal component of the liver microsomal stearyl-CoA desaturase system, that utilizes O(2) and electrons from reduced cytochrome b5 to catalyze the insertion of a double bond into a spectrum of fatty acyl-CoA substrates including palmitoyl-CoA and stearoyl-CoA. Belongs to the fatty acid desaturase family.

Protein type: Membrane protein, multi-pass; Oxidoreductase; Membrane protein, integral; EC 1.14.19.1; Endoplasmic reticulum; Lipid Metabolism - unsaturated fatty acid biosynthesis

Chromosomal Location of Human Ortholog: 10q24.31

Cellular Component: endoplasmic reticulum; endoplasmic reticulum membrane; integral to membrane; membrane

Molecular Function: iron ion binding; oxidoreductase activity; stearoyl-CoA 9-desaturase activity

Biological Process: unsaturated fatty acid biosynthetic process