Rabbit anti-SARS-CoV SARS Envelope Protein Polyclonal Antibody | anti-SARS antibody

SARS Envelope Protein Polyclonal Antibody

Cat. Num. AAA191604

• Reactivity: SARS-CoV
• Applications: ELISA
• Synonyms: SARS Envelope Protein; Polyclonal Antibody; SARS Envelope Protein Polyclonal Antibody; anti-SARS antibody

• Host: Rabbit
• Reactivity: SARS-CoV
• Clonality: Polyclonal
• Specificity: SARS-CoV envelope protein.
• Form/Format: Antibody purified by peptide affinity chromatography in PBS, 0.02% sodium azide

• Applicable Applications for anti-SARS antibody: ELISA (EIA)
• Application Notes: ELISA: Endusers should determine optimal antibody concentrations for their samples and assay formats.
• Antigen: Synthetic peptide corresponding to the amino-terminus of SARS-CoV envelope protein.
• Preparation and Storage: This antibody is stable for at least one (1) year at -20 degree C. Store product in appropriate aliquots to avoid multiple freeze-thaw cycles.

Related Product Information for anti-SARS antibody

Background: Severe acute respiratory syndrome (SARS) is a viral respiratory illness caused by a coronavirus referred to as SARS-associated coronavirus (SARS-CoV). SARS was first reported in Asia in February 2003. Over the next few months, the illness spread to more than two dozen countries in North America, South America, Europe, and Asia before the SARS global outbreak of 2003 was contained. SARS-CoV is transmitted from person to person by close personal contact such as via respiratory droplets produced when an infected person coughs or sneezes. The genomes of these viruses are positive-stranded RNA approximately 27-31kb long. The envelope (E) protein is the smallest of the major structural SARS proteins. During virus replication, E is expressed in the infected cell, but only a small portion of it is incorporated into the virus envelope. The majority of E protein is found at the site of intracellular trafficking (i.e. ER, Golgi) where it plays a role in virus assembly and budding.

Product Categories/Family for anti-SARS antibody

Antibody Products; Infectious Disease Antibodies; Products

NCBI and Uniprot Product Information

• NCBI GI #: 1791269092
• NCBI GeneID: 43740570
• UniProt Accession #: P59637
• NCBI Official Full Name: Envelope small membrane protein
• UniProt Protein Name: Envelope small membrane protein
• Protein Family: Serine--tRNA ligase
• UniProt Gene Name: E
• UniProt Synonym Gene Names: sM; E protein; sM protein
• UniProt Entry Name: VEMP_CVHSA

Uniprot Description

Plays a central role in virus morphogenesis and assembly. Acts as a viroporin and self-assembles in host membranes forming pentameric protein-lipid pores that allow ion transport. Activates the host NLRP3 inflammasome, leading to IL-1beta overproduction.