Immunohistochemistry (IHC)
(SARM1 / SARM (2ug/ml) was used in IHC to stain formalin-fixed, paraffin-embedded human tonsil, followed by biotinylated goat rabbit IgG secondary, alkaline phosphatase-streptavidin and chromogen.)
Rabbit anti-Human, Mouse SARM1 Polyclonal Antibody | anti-SARM1 antibody
SARM1 (Sterile alpha and TIR motif containing 1)
Gene Names
SARM1; SARM; SAMD2; FLJ36296; KIAA0524
Reactivity
Human, Mouse
Applications
Western Blot, Immunohistochemistry, Immunocytochemistry
Purity
Highly PurifiedPurified by Ion Exchange chromatography.
Synonyms
SARM1; Polyclonal Antibody; SARM1 (Sterile alpha and TIR motif containing 1); Anti -SARM1 (Sterile alpha and TIR motif containing 1); anti-SARM1 antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Specificity
Recognizes Human Sterile Alpha And TIR Motif Containing 1 (SARM1/KIAA0524). Species Crossreactivity: Human, Mouse.
Purity/Purification
Highly Purified
Purified by Ion Exchange chromatography.
Purified by Ion Exchange chromatography.
Form/Format
Supplied as a liquid in PBS, 0.02% sodium azide.
Applicable Applications for anti-SARM1 antibody
Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC)
Application Notes
Suitable for use in Immunocytochemistry, Western Blot and Immunohistochemistry.
Dilution: Immunohistochemistry: 2ug/ml
Western Blot: 0.5-2ug/ml
Dilution: Immunohistochemistry: 2ug/ml
Western Blot: 0.5-2ug/ml
Immunogen
Synthetic peptide, KLH-conjugated. Epitope: peptide corresponding to amino acids near the C-terminus of human SARM
Preparation and Storage
May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol (40-50%), aliquot and store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Immunohistochemistry (IHC)
(SARM1 / SARM (2ug/ml) was used in IHC to stain formalin-fixed, paraffin-embedded human tonsil, followed by biotinylated goat rabbit IgG secondary, alkaline phosphatase-streptavidin and chromogen.)
Immunohistochemistry (IHC)
(SARM1 / SARM (2ug/ml) was used in IHC to stain formalin-fixed, paraffin-embedded human tonsil, followed by biotinylated goat rabbit IgG secondary, alkaline phosphatase-streptavidin and chromogen.)
Product Categories/Family for anti-SARM1 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
79,388 Da
NCBI Official Full Name
sterile alpha and TIR motif-containing protein 1
NCBI Official Synonym Full Names
sterile alpha and TIR motif containing 1
NCBI Official Symbol
SARM1
NCBI Official Synonym Symbols
SARM; SAMD2; FLJ36296; KIAA0524
NCBI Protein Information
sterile alpha and TIR motif-containing protein 1; tir-1 homolog; OTTHUMP00000163322; SAM domain-containing protein 2; sterile alpha and Armadillo repeat protein; sterile alpha motif domain-containing protein 2; sterile alpha and HEAT/Armadillo motif protein, ortholog of Drosophila
UniProt Protein Name
Sterile alpha and TIR motif-containing protein 1
Protein Family
UniProt Gene Name
SARM1
UniProt Synonym Gene Names
KIAA0524; SAMD2; SARM
UniProt Entry Name
SARM1_HUMAN
Uniprot Description
SARM1: Involved in innate immnune response. Acts as a negative regulator of TICAM1/TRIF-dependent Toll-like receptor signaling by inhibiting induction of TLR3- and TLR4-dependent genes. Specifically blocks TICAM1/TRIF-dependent transcription-factor activation and gene induction, without affecting the MYD88- dependent pathway or non-TLR signaling. Negative regulator of NF- kappa-B and IRF activation. 2 isoforms of the human protein are produced by alternative splicing.
Chromosomal Location of Human Ortholog: 17q11
Cellular Component: microtubule; mitochondrion; axon; cytoplasm; dendrite; extrinsic to mitochondrial outer membrane; synapse; cytosol; cell junction
Biological Process: regulation of apoptosis; MyD88-independent toll-like receptor signaling pathway; regulation of dendrite morphogenesis; response to glucose stimulus; toll-like receptor signaling pathway; innate immune response; toll-like receptor 3 signaling pathway; toll-like receptor 4 signaling pathway
Research Articles on SARM1
1. Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
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Product Notes
The SARM1 sarm1 (Catalog #AAA611757) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The SARM1 (Sterile alpha and TIR motif containing 1) reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's SARM1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC). Suitable for use in Immunocytochemistry, Western Blot and Immunohistochemistry. Dilution: Immunohistochemistry: 2ug/ml Western Blot: 0.5-2ug/ml. Researchers should empirically determine the suitability of the SARM1 sarm1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SARM1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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