Western Blot (WB)
(Host: RabbitTarget Name: SAP130Sample Type: Jurkat Whole Cell lysatesAntibody Dilution: 1.0ug/mlSAP130 is supported by BioGPS gene expression data to be expressed in Jurkat)
Rabbit SAP130 Polyclonal Antibody | anti-SAP130 antibody
SAP130 Antibody - C-terminal region
Western Blot (WB)
(Host: RabbitTarget Name: SAP130Sample Type: Jurkat Whole Cell lysatesAntibody Dilution: 1.0ug/mlSAP130 is supported by BioGPS gene expression data to be expressed in Jurkat)
Western Blot (WB)
(Host: RabbitTarget Name: SAP130Sample Type: Jurkat Whole Cell lysatesAntibody Dilution: 1.0ug/mlSAP130 is supported by BioGPS gene expression data to be expressed in Jurkat)
Target Description: SAP130 is a subunit of the histone deacetylase-dependent SIN3A corepressor complex.
NCBI and Uniprot Product Information
NCBI Description
SAP130 is a subunit of the histone deacetylase (see HDAC1; MIM 601241)-dependent SIN3A (MIM 607776) corepressor complex (Fleischer et al., 2003 [PubMed 12724404]).[supplied by OMIM, Mar 2008]
Uniprot Description
SAP130: Acts as a transcriptional repressor. May function in the assembly and/or enzymatic activity of the mSin3A corepressor complex or in mediating interactions between the complex and other regulatory complexes. Belongs to the SAP130 family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Transcription factor; Acetyltransferase
Chromosomal Location of Human Ortholog: 2q14.3
Cellular Component: nucleoplasm
Molecular Function: histone acetyltransferase activity; transcription coactivator activity
Biological Process: establishment and/or maintenance of chromatin architecture; transcription, DNA-dependent; negative regulation of gene expression, epigenetic; gene expression; negative regulation of transcription from RNA polymerase II promoter; regulation of gene expression, epigenetic
Research Articles on SAP130
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Product Notes
The SAP130 sap130 (Catalog #AAA3211500) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The SAP130 Antibody - C-terminal region reacts with Cow, Dog, Horse, Human, Mouse, Pig, Rabbit, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's SAP130 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Researchers should empirically determine the suitability of the SAP130 sap130 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Synthetic peptide located within the following region: ANNLSMPTSD LPPGASPRKK PRKQQHVIST EEGDMMETNS TDDEKSTAKS. It is sometimes possible for the material contained within the vial of "SAP130, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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