Rabbit anti-Human SAMHD1 Polyclonal Antibody | anti-SAMHD1 antibody

SAMHD1, ID (SAMHD1, MOP5, SAM domain and HD domain-containing protein 1, Dendritic cell-derived IFNG-induced protein, Monocyte protein 5) (PE)

Cat. Num. AAA6344963

• Gene Names: SAMHD1; DCIP; CHBL2; HDDC1; MOP-5; SBBI88
• Reactivity: Human
• Applications: Western Blot
• Purity: Purified by Protein A and Peptide Affinity Chromatography.
• Synonyms: SAMHD1; Polyclonal Antibody; ID (SAMHD1; MOP5; SAM domain and HD domain-containing protein 1; Dendritic cell-derived IFNG-induced protein; Monocyte protein 5) (PE); Monocyte protein 5; anti-SAMHD1 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Recognizes human SAMHD1.
• Purity/Purification: Purified by Protein A and Peptide Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with R-Phycoerythrin (PE).

• Applicable Applications for anti-SAMHD1 antibody: Western Blot (WB), FLISA
• Application Notes: Applications are based on unconjugated antibody.
• Immunogen: KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 204-230 in the central region of human SAMHD1, UniProt Accession #Q9Y3Z3.
• Conjugate: PE
• Note: Preservative Free
• Special Handling: Light sensitive
• Preparation and Storage: Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: PE conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Western Blot (WB)

(Western Blot analysis in K562 cell line lysates (35ug/lane) usingMBS6010534.)

Related Product Information for anti-SAMHD1 antibody

This gene may play a role in regulation of the innate immune response. The encoded protein is upregulated in response to viral infection and may be involved in mediation of tumor necrosis factor-alpha proinflammatory responses. Mutations in this gene have been associated with Aicardi-Goutieres syndrome. [provided by RefSeq].

Product Categories/Family for anti-SAMHD1 antibody

Antibodies; Disease Markers

References

1. Tomkova, H., et al. Eur J Dermatol 20(3):411-413(2010). 2. Dale, R.C., et al. Am. J. Med. Genet. A 152A (4), 938-942 (2010). 3. Davila, S., et al. Genes Immun. 11(3):232-238(2010). 4. Rice, G.I., et al. Nat. Genet. 41(7):829-832(2009). 5. Liao, W., et al. Proteomics 8(13):2640-2650(2008).

NCBI and Uniprot Product Information

• NCBI GI #: 38016914
• NCBI GeneID: 25939
• NCBI Accession #: NP_056289.2
• NCBI GenBank Nucleotide #: NM_015474.3
• UniProt Accession #: Q9Y3Z3; Q5JXG8; Q8N491; Q9H004; Q9H005; Q9H3U9; B4E2A5; E1P5V2
• Molecular Weight: 68,122 Da
• NCBI Official Full Name: deoxynucleoside triphosphate triphosphohydrolase SAMHD1
• NCBI Official Synonym Full Names: SAM domain and HD domain 1
• NCBI Official Symbol: SAMHD1
• NCBI Official Synonym Symbols: DCIP; CHBL2; HDDC1; MOP-5; SBBI88
• NCBI Protein Information: deoxynucleoside triphosphate triphosphohydrolase SAMHD1
• UniProt Protein Name: Deoxynucleoside triphosphate triphosphohydrolase SAMHD1
• Protein Family: Deoxynucleoside triphosphate triphosphohydrolase
• UniProt Gene Name: SAMHD1
• UniProt Synonym Gene Names: MOP5; dNTPase; DCIP; MOP-5
• UniProt Entry Name: SAMH1_HUMAN

NCBI Description

This gene may play a role in regulation of the innate immune response. The encoded protein is upregulated in response to viral infection and may be involved in mediation of tumor necrosis factor-alpha proinflammatory responses. Mutations in this gene have been associated with Aicardi-Goutieres syndrome. [provided by RefSeq, Mar 2010]