Mouse anti-Human SAMD4A Polyclonal Antibody | anti-SAMD4A antibody

SAMD4A (Sterile alpha Motif Domain-containing Protein 4A, SAM domain-containing Protein 4A, SAMD4, KIAA1053, Protein Smaug Homolog 1, Smaug 1, SMAUG1, hSmaug1, SMAUG, SMG, SMGA)

Cat. Num. AAA649433

• Gene Names: SAMD4A; SMG; SMGA; SAMD4; SMAUG; SMAUG1
• Reactivity: Human
• Applications: Western Blot
• Purity: Affinity Purified; Purified by Protein A affinity chromatography.
• Synonyms: SAMD4A; Polyclonal Antibody; SAMD4A (Sterile alpha Motif Domain-containing Protein 4A; SAM domain-containing Protein 4A; SAMD4; KIAA1053; Protein Smaug Homolog 1; Smaug 1; SMAUG1; hSmaug1; SMAUG; SMG; SMGA); Anti -SAMD4A (Sterile alpha Motif Domain-containing Protein 4A; anti-SAMD4A antibody

• Host: Mouse
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Recognizes human SAMD4A.
• Purity/Purification: Affinity Purified; Purified by Protein A affinity chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2.
• Sequence: MMFRDQVGVLAGWFKGWNECEQTVALLSLLKRVSQTQARFLQLCLEHSLADCAELHVLEREANSPGIINQWQQESKDKVISLLLTHLPLLKPGNLDAKVEYMKLLPKTLAHSIEHNQHIEESRQLLSYALIHPATSLEDRSALAMWLNHLEDRTSTSFGGQNRGRSDSVDYGQTHYYHQRQNSDDKLNGWQNSRDSGICINASNWQDKSMGCENGHVPLYSSSSVPTTINTIGTSTSTSKFPGIPLT

• Applicable Applications for anti-SAMD4A antibody: Western Blot (WB)
• Application Notes: Suitable for use in Western Blot.
• Immunogen: Full length human SAMD4A, aa1-247 (AAH57838.1).
• Preparation and Storage: May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(Western Blot analysis of SAMD4A expression in transfected 293T cell line by SAMD4A polyclonal antibody. Lane 1: SAMD4A transfected lysate (27.17kD). Lane 2: Non-transfected lysate.)

Product Categories/Family for anti-SAMD4A antibody

Antibodies; Abs to DNA/RNA Translation

NCBI and Uniprot Product Information

• NCBI GI #: 111309274
• NCBI GeneID: 23034
• UniProt Accession #: Q9UPU9; Q0VA96; Q6PEW4; A8MPZ5
• Molecular Weight: 79,415 Da
• NCBI Official Full Name: SAMD4A protein
• NCBI Official Synonym Full Names: sterile alpha motif domain containing 4A
• NCBI Official Symbol: SAMD4A
• NCBI Official Synonym Symbols: SMG; SMGA; SAMD4; SMAUG; SMAUG1
• NCBI Protein Information: protein Smaug homolog 1; SAM domain-containing protein 4A
• UniProt Protein Name: Protein Smaug homolog 1
• Protein Family: Protein
• UniProt Gene Name: SAMD4A
• UniProt Synonym Gene Names: KIAA1053; SAMD4; SMAUG1; Smaug 1; hSmaug1
• UniProt Entry Name: SMAG1_HUMAN

NCBI Description

Sterile alpha motifs (SAMs) in proteins such as SAMD4A are part of an RNA-binding domain that functions as a posttranscriptional regulator by binding to an RNA sequence motif known as the Smaug recognition element, which was named after the Drosophila Smaug protein (Baez and Boccaccio, 2005 [PubMed 16221671]).[supplied by OMIM, Mar 2008]

Uniprot Description

Function: Acts as a translational repressor of SRE-containing messengers. Ref.6

Subcellular location: Cytoplasm. Cell projection › dendrite

By similarity. Cell junction › synapse › synaptosome

By similarity. Note: Enriched in synaptoneurosomes

By similarity. Shuttles between the nucleus and the cytoplasm in a CRM1-dependent manner. Colocalizes throughout the cytoplasm in granules with polyadenylated RNAs, PABPC1 and STAU1. Also frequently colocalizes in cytoplasmic stress granule-like foci with ELAVL1, TIA1 and TIAL1. Ref.6

Sequence similarities: Belongs to the SMAUG family.Contains 1 SAM (sterile alpha motif) domain.

Sequence caution: The sequence AAH57838.1 differs from that shown. Reason: Intron retention.The sequence AAP97302.1 differs from that shown. Reason: Intron retention.