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Western Blot (WB) (Western Blot analysis of Rat kidney tissue using S1PR4 Polyclonal Antibody at dilution of 1:250)

Rabbit S1PR4 Polyclonal Antibody | anti-S1PR4 antibody

S1PR4 Polyclonal Antibody

Gene Names
S1PR4; EDG6; LPC1; S1P4; SLP4
Reactivity
Human, Mouse, Rat
Applications
ELISA, Western Blot
Purity
Antigen affinity purification
Synonyms
S1PR4; Polyclonal Antibody; S1PR4 Polyclonal Antibody; EDG6; LPC1; S1P4; SLP4; anti-S1PR4 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen affinity purification
Concentration
0.5mg/mL (varies by lot)
Sequence Length
384
Applicable Applications for anti-S1PR4 antibody
ELISA (EIA), Western Blot (WB)
Application Notes
WB: 1:200-1:1000
Immunogen
Synthetic peptide of human S1PR4
Buffer
PBS with 0.05% sodium azide, 50% glycerol, pH7.3
Preparation and Storage
Store at -20 degree C (regular) and -80 degree C (long term). Avoid freeze / thaw cycles.

Western Blot (WB)

(Western Blot analysis of Rat kidney tissue using S1PR4 Polyclonal Antibody at dilution of 1:250)

Western Blot (WB) (Western Blot analysis of Rat kidney tissue using S1PR4 Polyclonal Antibody at dilution of 1:250)
Related Product Information for anti-S1PR4 antibody
This gene is a member of the endothelial differentiation, G-protein-coupled (EDG)) receptor gene family. EDG receptors bind lysophospholipids or lysosphingolipids as ligands, and are involved in cell signalling in many different cell types. This EDG receptor gene is intronless and is specifically expressed in the lymphoid tissue. Receptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
Molecular Weight
41,623 Da
NCBI Official Full Name
Sphingosine 1-phosphate receptor 4
NCBI Official Synonym Full Names
sphingosine-1-phosphate receptor 4
NCBI Official Symbol
S1PR4
NCBI Official Synonym Symbols
EDG6; LPC1; S1P4; SLP4
NCBI Protein Information
sphingosine 1-phosphate receptor 4; S1P receptor 4; S1P receptor Edg-6; endothelial differentiation G-protein coupled receptor 6; endothelial differentiation, G protein coupled receptor 6; endothelial differentiation, G-protein-coupled receptor 6; endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor, 6; sphingosine 1-phosphate receptor Edg-6
UniProt Protein Name
Sphingosine 1-phosphate receptor 4
UniProt Gene Name
S1PR4
UniProt Synonym Gene Names
EDG6; S1P receptor 4; S1P4; S1P receptor Edg-6
UniProt Entry Name
S1PR4_HUMAN

NCBI Description

This gene is a member of the endothelial differentiation, G-protein-coupled (EDG)) receptor gene family. EDG receptors bind lysophospholipids or lysosphingolipids as ligands, and are involved in cell signalling in many different cell types. This EDG receptor gene is intronless and is specifically expressed in the lymphoid tissue. [provided by RefSeq, Jul 2008]

Uniprot Description

S1PR4: Receptor for the lysosphingolipid sphingosine 1- phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. May be involved in cell migration processes that are specific for lymphocytes. Belongs to the G-protein coupled receptor 1 family.

Protein type: Receptor, GPCR; GPCR, family 1; Membrane protein, multi-pass; Membrane protein, integral

Chromosomal Location of Human Ortholog: 19p13.3

Cellular Component: integral to plasma membrane; plasma membrane

Molecular Function: G-protein coupled receptor activity; lipid binding

Biological Process: G-protein coupled receptor protein signaling pathway; elevation of cytosolic calcium ion concentration; phospholipase C activation; immune response; G-protein signaling, adenylate cyclase activating pathway

Research Articles on S1PR4

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Product Notes

The S1PR4 s1pr4 (Catalog #AAA2527777) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The S1PR4 Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's S1PR4 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB). WB: 1:200-1:1000. Researchers should empirically determine the suitability of the S1PR4 s1pr4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "S1PR4, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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