Western Blot (WB)
Rabbit anti-Human, Mouse S100 beta Polyclonal Antibody | anti-S100P antibody
S100 beta Antibody
Gene Names
S100P; MIG9
Reactivity
Human, Mouse
Applications
ELISA, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blot
Synonyms
S100 beta; Polyclonal Antibody; S100 beta Antibody; NEF; S 100 calcium binding protein beta chain; S 100 protein beta chain; S 100 protein beta subunit; S100 calcium-binding protein B antibody; anti-S100P antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Form/Format
Affinity Purified
Concentration
0.65 ug/ul in antibody stabilization buffer (varies by lot)
Sequence Length
95
Applicable Applications for anti-S100P antibody
Confocal Microscopy (CM), ELISA (EIA), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB)
Application Notes
Dot Blot: 1:10,000
ELISA: 1:10,000
Western Blot: 1:500
ELISA: 1:10,000
Western Blot: 1:500
Immunogen
Full length protein of human S100 beta/beta homodimer.
Expression
Detected in all of the tissues except brain, testis and small intestine, expression level is higher in placenta, heart, lung, skeletal muscle, spleen and leukocyte. Up-regulated in various pancreatic ductal adenocarcinomas and pancreatic intraepithelial neoplasias.
Molecular Function
Calcium-dependent protein binding, calcium ion binding, magnesium ion binding
Structure
Homodimer and heterodimer with S100A1. Interacts with S100PBP and S100Z. Interacts with CACYBP in a calcium-dependent manner. Dimeric form binds to and activates EZR/Ezrin by unmasking its F-actin binding sites. Interacts with PPP5C (via TPR repeats); the interaction is calcium-dependent and modulates PPP5C activity.
Subcellular Location
Nucleus, Cytoplasm, Cell projection ; Microvillus membrane
Preparation and Storage
-20 degree C for long term storage
Western Blot (WB)
Western Blot (WB)
Related Product Information for anti-S100P antibody
May function as calcium sensor and contribute to cellular calcium signaling. In a calcium-dependent manner, functions by interacting with other proteins, such as EZR and PPP5C, and indirectly plays a role in physiological processes like the formation of microvilli in epithelial cells. May stimulate cell proliferation in an autocrine manner via activation of the receptor for activated glycation end products (RAGE).
Product Categories/Family for anti-S100P antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
10,400 Da
NCBI Official Full Name
Protein S100-P
NCBI Official Synonym Full Names
S100 calcium binding protein P
NCBI Official Symbol
S100P
NCBI Official Synonym Symbols
MIG9
NCBI Protein Information
protein S100-P
UniProt Protein Name
Protein S100-P
Protein Family
UniProt Gene Name
S100P
UniProt Synonym Gene Names
S100E; MIG9
UniProt Entry Name
S100P_HUMAN
NCBI Description
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21; however, this gene is located at 4p16. This protein, in addition to binding Ca2+, also binds Zn2+ and Mg2+. This protein may play a role in the etiology of prostate cancer. [provided by RefSeq, Jul 2008]
Uniprot Description
May function as calcium sensor and contribute to cellular calcium signaling. In a calcium-dependent manner, functions by interacting with other proteins, such as EZR and PPP5C, and indirectly plays a role in physiological processes like the formation of microvilli in epithelial cells. May stimulate cell proliferation in an autocrine manner via activation of the receptor for activated glycation end products (RAGE).
Research Articles on S100P
Similar Products
Product Notes
The S100P s100p (Catalog #AAA540112) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The S100 beta Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's S100 beta can be used in a range of immunoassay formats including, but not limited to, Confocal Microscopy (CM), ELISA (EIA), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB). Dot Blot: 1:10,000 ELISA: 1:10,000 Western Blot: 1:500. Researchers should empirically determine the suitability of the S100P s100p for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "S100 beta, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
