Testing Data
(Gel: 10%SDS-PAGE Lysate: 40ug Jurkat cell Primary antibody: 1/350 dilution Secondary antibody dilution: 1/8000 Exposure time: 10 minutes)
Rabbit anti-Human, Mouse RXFP3 Polyclonal Antibody | anti-RXFP3 antibody
RXFP3 Antibody
Gene Names
RXFP3; SALPR; RLN3R1; RXFPR3; GPCR135
Reactivity
Human, Mouse
Applications
Western Blot, Immunohistochemistry
Purity
Antigen affinity purification.
Synonyms
RXFP3; Polyclonal Antibody; RXFP3 Antibody; SALPR; RLN3R1; RXFPR3; GPCR135; anti-RXFP3 antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Specificity
The antibody detects endogenous levels of total RXFP3 protein.
Purity/Purification
Antigen affinity purification.
Form/Format
Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
Concentration
0.7 mg/ml (varies by lot)
Sequence Length
469
Applicable Applications for anti-RXFP3 antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
Western blotting: 1:200-1:1000
Immunohistochemistry: 1:25-1:100
Immunohistochemistry: 1:25-1:100
Immunogen Type
Peptide
Immunogen Description
Synthetic peptide corresponding to residues near the C terminal of human Relaxin/insulin-like family peptide receptor 3
Target Name
RXFP3
Preparation and Storage
Store at -20 degree C
Testing Data
(Gel: 10%SDS-PAGE Lysate: 40ug Jurkat cell Primary antibody: 1/350 dilution Secondary antibody dilution: 1/8000 Exposure time: 10 minutes)
Testing Data
(Gel: 10%SDS-PAGE Lysate: 40ug Jurkat cell Primary antibody: 1/350 dilution Secondary antibody dilution: 1/8000 Exposure time: 10 minutes)
Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded Human thyroid cancer tissue using at dilution 1/20.)
Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded Human thyroid cancer tissue using at dilution 1/20.)
Related Product Information for anti-RXFP3 antibody
Relaxin/insulin-like family peptide receptor 3, also known as RXFP3, is a human G-protein coupled receptor. Receptor for RNL3/relaxin-3. Binding of the ligand inhibit cAMP accumulation. Expressed predominantly in brain regions. Highest expression in substantia nigra and pituitary, followed by hippocampus, spinal cord, amygdala, caudate nucleus and corpus callosum, quite low level in cerebellum. In peripheral tissues, relatively high levels in adrenal glands, low levels in pancreas, salivary gland, placenta, mammary gland and testis.
Product Categories/Family for anti-RXFP3 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
51,124 Da
NCBI Official Full Name
relaxin-3 receptor 1
NCBI Official Synonym Full Names
relaxin/insulin-like family peptide receptor 3
NCBI Official Symbol
RXFP3
NCBI Official Synonym Symbols
SALPR; RLN3R1; RXFPR3; GPCR135
NCBI Protein Information
relaxin-3 receptor 1
UniProt Protein Name
Relaxin-3 receptor 1
Protein Family
UniProt Gene Name
RXFP3
UniProt Synonym Gene Names
RLN3R1; SALPR; RLN3 receptor 1
UniProt Entry Name
RL3R1_HUMAN
Uniprot Description
RLN3R1: Receptor for RNL3/relaxin-3. Binding of the ligand inhibit cAMP accumulation. Belongs to the G-protein coupled receptor 1 family.
Protein type: Membrane protein, multi-pass; GPCR, family 1; Receptor, GPCR; Membrane protein, integral
Chromosomal Location of Human Ortholog: 5p15.1-p14
Cellular Component: integral to plasma membrane; plasma membrane
Molecular Function: G-protein coupled receptor activity; peptide receptor activity, G-protein coupled
Biological Process: positive regulation of cytokinesis; G-protein coupled receptor protein signaling pathway; elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating)
Research Articles on RXFP3
Similar Products
Product Notes
The RXFP3 rxfp3 (Catalog #AAA9404227) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The RXFP3 Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's RXFP3 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC). Western blotting: 1:200-1:1000 Immunohistochemistry: 1:25-1:100. Researchers should empirically determine the suitability of the RXFP3 rxfp3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "RXFP3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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