Rabbit RSU1 Polyclonal Antibody | anti-RSU1 antibody

RSU1 Rabbit pAb

Cat. Num. AAA4759162

• Gene Names: RSU1; RSP-1
• Reactivity: Human, Mouse, Rat
• Applications: Western Blot, Immunohistochemistry
• Purity: Affinity purified
• Synonyms: RSU1; Polyclonal Antibody; RSU1 Rabbit pAb; Ras suppressor protein 1; RSP-1; anti-RSU1 antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Affinity purified
• Form/Format: pH7.4 PBS, 0.05% NaN3, 40% Glycerol
• Concentration: 0.96mg/ml (varies by lot)

• Applicable Applications for anti-RSU1 antibody: Western Blot (WB), Immunohistochemistry-Paraffin (IHC-P)
• Application Notes: WB: 1:500-1:2000; IHC-P: 1:25-1:100
• Immunogen: Fusion protein of human RSU1
• Conjugation: Unconjugated
• Modification: Unmodified
• Preparation and Storage: Store at 4 degree C for short term. Store at -20 degree C for long term. Avoid freeze/thaw cycle.

Western Blot (WB)

(Western Blot analysis of RSU1 in Rat heart tissue, Mouse heart tissue, Rat brain tissue, Mouse brain tissue, HEPG2 cell, Jurkat and Lovo cell lysates in order using RSU1 Rabbit pAb at dilution 1/400)

Immunohistochemistry (IHC)

(Immunohistochemistry of RSU1 in paraffin-embedded Human liver cancer tissue using RSU1 Rabbit pAb at dilution 1/30. Predicted cell location: Cytoplasm or Nucleus)

Related Product Information for anti-RSU1 antibody

This gene encodes a protein that is involved in the Ras signal transduction pathway, growth inhibition, and nerve-growth factor induced differentiation processes, as determined in mouse and human cell line studies. In mouse, the encoded protein was initially isolated based on its ability to inhibit v-Ras transformation. Multiple alternatively spliced transcript variants for this gene have been reported; one of these variants was found only in glioma tumors.

NCBI and Uniprot Product Information

• NCBI GI #: 2498866
• NCBI GeneID: 6251
• UniProt Accession #: Q15404; Q6FI17; A8KA46; D3DRU3
• Molecular Weight: 277
• NCBI Official Full Name: Ras suppressor protein 1
• NCBI Official Synonym Full Names: Ras suppressor protein 1
• NCBI Official Symbol: RSU1
• NCBI Official Synonym Symbols: RSP-1
• NCBI Protein Information: ras suppressor protein 1; rsu-1; ras suppressor protein 1 variant 1; ras suppressor protein 1 variant 2; ras suppressor protein 1 variant 3
• UniProt Protein Name: Ras suppressor protein 1
• Protein Family: Ras suppressor protein
• UniProt Gene Name: RSU1
• UniProt Synonym Gene Names: RSP1; RSP-1; Rsu-1
• UniProt Entry Name: RSU1_HUMAN

NCBI Description

This gene encodes a protein that is involved in the Ras signal transduction pathway, growth inhibition, and nerve-growth factor induced differentiation processes, as determined in mouse and human cell line studies. In mouse, the encoded protein was initially isolated based on its ability to inhibit v-Ras transformation. Multiple alternatively spliced transcript variants for this gene have been reported; one of these variants was found only in glioma tumors. [provided by RefSeq, Jul 2008]

Uniprot Description

RSU1: a leucine-rich protein that interacts with the IPP (integrin-linked kinase (ILK)/PINCH1/ parvin) focal adhesion complex. Plays a role in Ras signaling pathways. Capable of suppressing v-Ras transformation in vitro

Protein type: Cell adhesion

Chromosomal Location of Human Ortholog: 10p13

Cellular Component: focal adhesion; cytosol

Molecular Function: protein binding

Biological Process: Ras protein signal transduction; signal transduction; positive regulation of GTPase activity