Western Blot (WB)
(Western Blot (WB) analysis of RRS1 (R286) pAb at 1:1000 dilutionLane1:EC9706 whole cell lysate (10ug) Lane2:A375 whole cell lysate (10ug))
Rabbit anti-Human RRS1 Polyclonal Antibody | anti-RRS1 antibody
RRS1 (R286) Polyclonal Antibody
Reactivity
Human
Applications
Western Blot, Immunohistochemistry
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
Synonyms
RRS1; Polyclonal Antibody; RRS1 (R286) Polyclonal Antibody; Homolog of yeast ribosome biogenesis regulator; Homolog of yeast ribosome biogenesis regulatory protein RRS1; KIAA0112; OTTHUMP00000227420; Ribosome biogenesis regulatory protein homolog; Ribosome biogenesis regulatory protein RRS1 homolog; RRR; rrs1; anti-RRS1 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
RRS1 (R286) polyclonal antibody detects endogenous levels of RRS1 protein.
Purity/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
Form/Format
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Sequence Length
365
Applicable Applications for anti-RRS1 antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
WB: 1:500-1:1000
IHC: 1:50-1:200
IHC: 1:50-1:200
Immunogen
Synthetic peptide, corresponding to amino acids 255-307 of Human RRS1.
Preparation and Storage
Store at 4 degree C short term.
Aliquot and store at -20 degree C long term.
Avoid freeze-thaw cycles.
Aliquot and store at -20 degree C long term.
Avoid freeze-thaw cycles.
Western Blot (WB)
(Western Blot (WB) analysis of RRS1 (R286) pAb at 1:1000 dilutionLane1:EC9706 whole cell lysate (10ug) Lane2:A375 whole cell lysate (10ug))
Western Blot (WB)
(Western Blot (WB) analysis of RRS1 (R286) pAb at 1:1000 dilutionLane1:EC9706 whole cell lysate (10ug) Lane2:A375 whole cell lysate (10ug))
Immunohistochemistry (IHC)
(Immunohistochemistry (IHC) analyzes of RRS1 (R286) pAb in paraffin-embedded human breast carcinoma tissue at 1:100.)
Immunohistochemistry (IHC)
(Immunohistochemistry (IHC) analyzes of RRS1 (R286) pAb in paraffin-embedded human breast carcinoma tissue at 1:100.)
Related Product Information for anti-RRS1 antibody
RRS1, also known as KIAA0112, ribosome biogenesis regulatory protein homolog, regulator of ribosome synthesis 1, ribosome biogenesis regulatory protein RRS1 homolog or RRR, is a 365 amino acid protein belonging to the RRS1 family. RRS1 shows nucleolar localization and is involved in both ribosome biogenesis and chromosome congression. Recent studies indicate that in the absence of RRS1, cells experience mitotic delay due to abnormal spindle organization and chromosome alignment. The gene encoding RRS1 maps to human chromosome 8q13.1. Consisting of nearly 146 million base pairs, chromosome 8 encodes over 800 genes and is associated with a variety of diseases and malignancies. Schizophrenia, bipolar disorder, Trisomy 8, Pfeiffer syndrome, congenital hypothyroidism, Waardenburg syndrome and some leukemias and lymphomas are thought to occur as a result of defects in specific genes that map to chromosome 8.
NCBI and Uniprot Product Information
NCBI GI #
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
~ 45kDa
NCBI Official Full Name
ribosome biogenesis regulatory protein homolog
UniProt Protein Name
Ribosome biogenesis regulatory protein homolog
Protein Family
UniProt Gene Name
RRS1
UniProt Synonym Gene Names
KIAA0112; RRR
UniProt Entry Name
RRS1_HUMAN
Uniprot Description
RRS1: Involved in ribosome biogenesis. Belongs to the RRS1 family.
Protein type: Nucleolus; RNA processing; RNA-binding
Chromosomal Location of Human Ortholog: 8q13.1
Cellular Component: condensed nuclear chromosome; endoplasmic reticulum; nucleolus; nucleus
Biological Process: ribosome biogenesis and assembly; hemopoietic progenitor cell differentiation; mitotic metaphase plate congression
Similar Products
Product Notes
The RRS1 rrs1 (Catalog #AAA3004461) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The RRS1 (R286) Polyclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's RRS1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC). WB: 1:500-1:1000 IHC: 1:50-1:200. Researchers should empirically determine the suitability of the RRS1 rrs1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "RRS1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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