Rabbit RRAS2 Polyclonal Antibody | anti-RRAS2 antibody

RRAS2 Rabbit Polyclonal

Cat. Num. AAA7603723

• Gene Names: Rras2; TC21; C86394; 2610016H24Rik
• Reactivity: Human, Mouse, Rat
• Applications: ELISA, Western Blot, Immunohistochemistry, Immunofluorescence
• Purity: >=95% as determined by SDS-PAGE; Immunogen Affinity Purified
• Synonyms: RRAS2; Polyclonal Antibody; RRAS2 Rabbit Polyclonal; anti-RRAS2 antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: >=95% as determined by SDS-PAGE; Immunogen Affinity Purified
• Form/Format: Liquid
• Sequence Length: 204

• Applicable Applications for anti-RRAS2 antibody: ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
• Immunogen: Related RAS viral (r-ras) oncogene homolog 2
• Preparation and Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20 degree C for 24 months (Avoid repeated freeze / thaw cycles.)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human lung cancer tissue slide using MBS7603723 (RRAS2 Antibody) at dilution of 1:50)

Western Blot (WB)

(NIH/3T3 cells were subjected to SDS PAGE followed by western blot with MBS7603723 (RRAS2 antibody) at dilution of 1:800)

NCBI and Uniprot Product Information

• NCBI GI #: 165972315
• NCBI GeneID: 66922
• NCBI Accession #: NP_080122.2
• NCBI GenBank Nucleotide #: NM_025846.2
• Molecular Weight: 23,400 Da
• NCBI Official Full Name: ras-related protein R-Ras2
• NCBI Official Synonym Full Names: related RAS viral (r-ras) oncogene 2
• NCBI Official Symbol: Rras2
• NCBI Official Synonym Symbols: TC21; C86394; 2610016H24Rik
• NCBI Protein Information: ras-related protein R-Ras2
• UniProt Protein Name: Ras-related protein R-Ras2
• Protein Family: Ras-related protein
• UniProt Gene Name: Rras2
• UniProt Entry Name: RRAS2_MOUSE

Uniprot Description

RRas2: It is a plasma membrane-associated GTP-binding protein with GTPase activity. Might transduce growth inhibitory signals across the cell membrane, exerting its effect through an effector shared with the Ras proteins but in an antagonistic fashion. Defects in RRAS2 are a cause of susceptibility to ovarian cancer (OC). The term ovarian cancer defines common malignancies originating from ovarian tissue. Although many histologic types of ovarian tumors have been described, epithelial ovarian carcinoma is the most common form. Ovarian cancers are often asymptomatic and the recognized signs and symptoms, even of late-stage disease, are vague. Consequently, most patients are diagnosed with advanced disease. Belongs to the small GTPase superfamily. Ras family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: G protein, monomeric; Motility/polarity/chemotaxis; Oncoprotein; G protein; G protein, monomeric, Ras

Cellular Component: focal adhesion; intracellular; membrane; plasma membrane

Molecular Function: GTP binding; nucleotide binding; protein binding

Biological Process: cellular process; osteoblast differentiation; positive regulation of cell migration; Ras protein signal transduction; signal transduction; small GTPase mediated signal transduction